作者
Thibault Passeri, Paolo di Russo, Pierre-Olivier Champagne, Anne-Laure Bernat, Jérome Cartailler, Jean Pierre Guichard, Hamid Mammar, Lorenzo Giammattei, Homa Adle-Biassette, Bernard George, Emmanuel Mandonnet, Sébastien Froelich
发表日期
2021/8/1
期刊
Neurosurgery
卷号
89
期号
2
页码范围
291-299
出版商
LWW
简介
BACKGROUND
Currently, different postoperative predictors of chordoma recurrence have been identified. Tumor growth rate (TGR) is an image-based calculation that provides quantitative information of tumor's volume changing over time and has been shown to predict progression-free survival (PFS) in other tumor types.
OBJECTIVE
To explore the usefulness of TGR as a new preoperative radiological marker for chordoma recurrence.
METHODS
A retrospective single-institution study was carried out including patients reflecting these criteria: confirmed diagnosis of chordoma on pathological analysis, no history of previous radiation, and at least 2 preoperative thin-slice magnetic resonance images available to measure TGR. TGR was calculated for all patients, showing the percentage change in tumor size over 1 mo.
RESULTS
A total of 32 patients were retained for analysis. Patients with a TGR≥ 10.12%/m had a …
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