作者
Edward Tang Qian, Cheryl L Gatto, Olga Amusina, Mary Lynn Dear, William Hiser, Reagan Buie, Sunil Kripalani, Frank E Harrell, Robert E Freundlich, Yue Gao, Wu Gong, Cassandra Hennessy, Jillann Grooms, Megan Mattingly, Shashi K Bellam, Jessica Burke, Arwa Zakaria, Eduard E Vasilevskis, Frederic T Billings, Jill M Pulley, Gordon R Bernard, Christopher J Lindsell, Todd W Rice, Robert Dittus, Shon Dwyer, Paul Harris, Tina Hartert, Jim Hayman, Catherine Ivory, Kevin Johnson, Ruth Kleinpell, Lee Ann Liska, Patrick Luther, Jay Morrison, Thomas Nantais, Mariann Piano, Kris Rhem, Russell Rothman, Matt Semler, Robin Steaban, Philip Walker, Consuelo Wilkins, Adam Wright, Autumn Zuckerman, Vanderbilt Learning Healthcare System Platform Investigators
发表日期
2022/6/1
期刊
JAMA internal medicine
卷号
182
期号
6
页码范围
612-621
出版商
American Medical Association
简介
Importance
Awake prone positioning may improve hypoxemia among patients with COVID-19, but whether it is associated with improved clinical outcomes remains unknown.
Objective
To determine whether the recommendation of awake prone positioning is associated with improved outcomes among patients with COVID-19–related hypoxemia who have not received mechanical ventilation.
Design, Setting, and Participants
This pragmatic nonrandomized controlled trial was conducted at 2 academic medical centers (Vanderbilt University Medical Center and NorthShore University HealthSystem) during the COVID-19 pandemic. A total of 501 adult patients with COVID-19–associated hypoxemia who had not received mechanical ventilation were enrolled from May 13 to December 11, 2020.
Interventions
Patients were assigned 1:1 to receive either the practitioner-recommended awake prone positioning intervention …
学术搜索中的文章
ET Qian, CL Gatto, O Amusina, ML Dear, W Hiser… - JAMA internal medicine, 2022