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Drought is considered one of the major obstacles for agricultural productivity worldwide such that greater efforts are required to boost crop production under this stress. One of the methods to overcome this obstacle is to harness the potential of microbe-induced systemic tolerance against moisture stress. The present work evaluated the potential role of two bacterial strains, namely Bacillus altitudinis FD48 and Bacillus methylotrophicus RABA6 and their combination as a co-inoculant for promoting plant growth and moisture stress resilience in two contrast cultivars of Oryza sativa L: CO51 (moderately drought tolerant) and IR64 (drought susceptible) under conditions of terminal moisture stress. B. altitudinis FD48- and B. methylotrophicus-primed rice seeds (CO51 and IR64) significantly influenced the source-sink relationship and reduced the relative water content (RWC). While photosynthetic pigments and proline …