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The frequency and nature of spurious pulse oximetry readings were compared using both a conventional pulse oximeter (CPO) and a prototype Masimo signal extraction technology pulse oximeter (Masimo SET Trademark). At a university hospital, 50 ASA physical status I-IV adult patients who underwent general or spinalepidural anesthesia were selected from a group of 250 patients on the basis of high-alarm generation with routine postoperative pulse oximetry. Pulse oximetry data were recorded simultaneously from both devices with a computer. Overall, the CPO alarm frequency (ie, oxygen saturation< 90%, or complete signal loss) was once every 13 min, and 87% of these alarms were considered false. Alarms were considered false based on reference electrocardiographs (16 patients), arterial blood gases (7 patients), and clinical assessment. The prototype Masimo SET Trademark device alarm frequency …