作者
Vasiliki Pavlou, Sofia Cienfuegos, Shuhao Lin, Mark Ezpeleta, Kathleen Ready, Sarah Corapi, Jackie Wu, Jason Lopez, Kelsey Gabel, Lisa Tussing-Humphreys, Vanessa M Oddo, Shaina J Alexandria, Julienne Sanchez, Terry Unterman, Lisa S Chow, Alaina P Vidmar, Krista A Varady
发表日期
2023/10/2
期刊
JAMA network open
卷号
6
期号
10
页码范围
e2339337-e2339337
出版商
American Medical Association
简介
Importance
Time-restricted eating (TRE) has become increasingly popular, yet longer-term randomized clinical trials have not evaluated its efficacy and safety in patients with type 2 diabetes (T2D).
Objective
To determine whether TRE is more effective for weight reduction and glycemic control than daily calorie restriction (CR) or a control condition in adults with T2D.
Design, Setting, and Participants
This 6-month, parallel-group, randomized clinical trial was performed between January 25, 2022, and April 1, 2023, at the University of Illinois Chicago. Participants were aged 18 to 80 years with obesity and T2D. Data analysis was based on intention to treat.
Interventions
Participants were randomized to 1 of 3 groups: 8-hour TRE (eating 12 to 8pmonly, without calorie counting), CR (25% energy restriction daily), or control.
Main Outcomes and Measures
The primary outcome measure was change in body weight by month 6 …
学术搜索中的文章
V Pavlou, S Cienfuegos, S Lin, M Ezpeleta, K Ready… - JAMA network open, 2023