作者
Thomas Santo, Brodie Clark, Matt Hickman, Jason Grebely, Gabrielle Campbell, Luis Sordo, Aileen Chen, Lucy Thi Tran, Chrianna Bharat, Prianka Padmanathan, Grainne Cousins, Julie Dupouy, Erin Kelty, Roberto Muga, Bohdan Nosyk, Jeong Min, Raimondo Pavarin, Michael Farrell, Louisa Degenhardt
发表日期
2021/9/1
来源
JAMA psychiatry
卷号
78
期号
9
页码范围
979-993
出版商
American Medical Association
简介
Importance
Mortality among people with opioid dependence is higher than that of the general population. Opioid agonist treatment (OAT) is an effective treatment for opioid dependence; however, there has not yet been a systematic review on the relationship between OAT and specific causes of mortality.
Objective
To estimate the association of time receiving OAT with mortality.
Data Sources
The Embase, MEDLINE, and PsycINFO databases were searched through February 18, 2020, including clinical trial registries and previous Cochrane reviews.
Study Selection
All observational studies that collected data on all-cause or cause-specific mortality among people with opioid dependence while receiving and not receiving OAT were included. Randomized clinical trials (RCTs) were also included.
Data Extraction and Synthesis
This systematic review and meta-analysis followed the Preferred Reporting Items for Systematic …
学术搜索中的文章
T Santo, B Clark, M Hickman, J Grebely, G Campbell… - JAMA psychiatry, 2021