作者
Carmen FA Eustatia-Rutten, Eleonora PM Corssmit, Nienke R Biermasz, Alberto M Pereira, Johannes A Romijn, Johannes W Smit
发表日期
2006/1/1
期刊
The Journal of Clinical Endocrinology & Metabolism
卷号
91
期号
1
页码范围
313-319
出版商
Oxford University Press
简介
Background: Survival studies in differentiated thyroid carcinoma (DTC) may be biased because they have been performed in heterogeneous populations. In addition, specific death causes in DTC have not been documented well in the literature.
Aims: The aim of our study was to investigate survival and specific death causes in a homogeneous cohort of DTC patients.
Patients: Patients included 366 consecutive patients with DTC who had all been treated according to the same protocol for initial therapy and follow-up.
Methods: Prognostic factors for DTC-related death were analyzed by univariate Cox regression analysis, followed by stepwise multivariate Cox regression analysis. Standardized mortality rates (SMR) were calculated using normal mortality rates for the entire Dutch population.
Results: During follow-up of 8.3 ± 4.6 yr, 82 patients (22.4%) died. At …
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