作者
Helen M Parsons, Todd M Tuttle, Karen M Kuntz, James W Begun, Patricia M McGovern, Beth A Virnig
发表日期
2011/9/14
期刊
Jama
卷号
306
期号
10
页码范围
1089-1097
出版商
American Medical Association
简介
Context
Among patients surgically treated for colon cancer, better survival has been demonstrated in those with more lymph nodes evaluated. The presumed mechanism behind this association suggests that a more extensive lymph node evaluation reduces the risk of understaging, leading to improved survival.
Objective
To further evaluate the mechanism behind lymph node evaluation and survival by examining the association between more extensive lymph node evaluation, identification of lymph node–positive cancers, and hazard of death.
Design
Observational cohort study.
Setting
Surveillance, Epidemiology, and End Results (SEER) program data from 1988 through 2008.
Patients
86 394 patients surgically treated for colon cancer.
Main Outcome Measure
We examined the relationship between lymph node evaluation and node positivity using Cochran-Armitage tests and multivariate logistic regression. The …
学术搜索中的文章
HM Parsons, TM Tuttle, KM Kuntz, JW Begun… - Jama, 2011