作者
Jean-Louis Vincent, Jordi Rello, John Marshall, Eliezer Silva, Antonio Anzueto, Claude D Martin, Rui Moreno, Jeffrey Lipman, Charles Gomersall, Yasser Sakr, Konrad Reinhart, xx EPIC II Group of Investigators
发表日期
2009/12/2
期刊
Jama
卷号
302
期号
21
页码范围
2323-2329
出版商
American Medical Association
简介
Context
Infection is a major cause of morbidity and mortality in intensive care units (ICUs) worldwide. However, relatively little information is available about the global epidemiology of such infections.
Objective
To provide an up-to-date, international picture of the extent and patterns of infection in ICUs.
Design, Setting, and Patients
The Extended Prevalence of Infection in Intensive Care (EPIC II) study, a 1-day, prospective, point prevalence study with follow-up conducted on May 8, 2007. Demographic, physiological, bacteriological, therapeutic, and outcome data were collected for 14 414 patients in 1265 participating ICUs from 75 countries on the study day. Analyses focused on the data from the 13 796 adult (>18 years) patients.
Results
On the day of the study, 7087 of 13 796 patients (51%) were considered infected; 9084 (71%) were receiving antibiotics. The infection was of respiratory origin in 4503 (64%), and …
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JL Vincent, J Rello, J Marshall, E Silva, A Anzueto… - Jama, 2009