作者
Geraldine Dawson, Emily JH Jones, Kristen Merkle, Kaitlin Venema, Rachel Lowy, Susan Faja, Dana Kamara, Michael Murias, Jessica Greenson, Jamie Winter, Milani Smith, Sally J Rogers, Sara J Webb
发表日期
2012/11/1
期刊
Journal of the American Academy of Child & Adolescent Psychiatry
卷号
51
期号
11
页码范围
1150-1159
出版商
Elsevier
简介
OBJECTIVE
A previously published randomized clinical trial indicated that a developmental behavioral intervention, the Early Start Denver Model (ESDM), resulted in gains in IQ, language, and adaptive behavior of children with autism spectrum disorder. This report describes a secondary outcome measurement from this trial, EEG activity.
METHOD
Forty-eight 18- to 30-month-old children with autism spectrum disorder were randomized to receive the ESDM or referral to community intervention for 2 years. After the intervention (age 48 to 77 months), EEG activity (event-related potentials and spectral power) was measured during the presentation of faces versus objects. Age-matched typical children were also assessed.
RESULTS
The ESDM group exhibited greater improvements in autism symptoms, IQ, language, and adaptive and social behaviors than the community intervention group. The ESDM group and …
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G Dawson, EJH Jones, K Merkle, K Venema, R Lowy… - Journal of the American Academy of Child & …, 2012