作者
Katrina E Donahue, Gerald Gartlehner, Daniel E Jonas, Linda J Lux, Patricia Thieda, Beth L Jonas, Richard A Hansen, Laura C Morgan, Kathleen N Lohr
发表日期
2008/1/15
来源
Annals of internal medicine
卷号
148
期号
2
页码范围
124-134
出版商
American College of Physicians
简介
Background
The comparative effectiveness of rheumatoid arthritis therapies is uncertain.
Purpose
To compare the benefits and harms of disease-modifying antirheumatic drugs (DMARDs) for adults with rheumatoid arthritis.
Data Sources
Records limited to the English language and studies of adults were identified by using MEDLINE, EMBASE, The Cochrane Library, and International Pharmaceutical Abstracts from 1980 to September 2007.
Study Selection
Two persons independently selected relevant head-to-head trials and prospective cohort studies with at least 100 participants and 12-week follow-up and relevant good- or fair-quality meta-analyses that compared benefits or harms of 11 drug therapies. For harms, they included retrospective cohort studies.
Data Extraction …
引用总数
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