作者
Andreas D Knudsen, Andreas Ronit, Thomas Kristensen, Magda Teresa Thomsen, Anne-Mette Lebech, Michael Huy Cuong, Per Ejlstrup Sigvardsen, Jørgen Tobias Kühl, Andreas Fuchs, Lars Køber, Jens Lundgren, Jørgen Vestbo, Klaus F Kofoed, Susanne D Nielsen
发表日期
2021/1/1
期刊
The Journal of infectious diseases
卷号
223
期号
1
页码范围
94-100
出版商
Oxford University Press
简介
Background
Pulmonary artery enlargement is a marker of pulmonary hypertension. We aimed to determine the proportion with pulmonary artery enlargement among well-treated persons with human immunodeficiency virus HIV (PWH) and uninfected controls.
Methods
PWH with a chest computed tomography were included from the ongoing Copenhagen Comorbidity in HIV Infection (COCOMO) study. Age and sex-matched uninfected controls were recruited from the Copenhagen General Population Study. Pulmonary artery enlargement was defined as a ratio of >1 between the diameter of the main pulmonary artery (at the level of its bifurcation) and the diameter of the ascending aorta.
Results
In total, 900 PWH were included, and 44 (5%) had a pulmonary artery–aorta ratio (PA:A) >1. After adjustment for age, sex, and body mass index, obesity (adjusted …
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AD Knudsen, A Ronit, T Kristensen, MT Thomsen… - The Journal of infectious diseases, 2021