作者
Emma LR Møller, Maria G Hauge, Michael HC Pham, Peter Damm, Klaus F Kofoed, Andreas Fuchs, Jørgen T Kühl, Per E Sigvardsen, Anne S Ersbøll, Marianne Johansen, Børge G Nordestgaard, Lars V Køber, Finn Gustafsson, Jesper J Linde
发表日期
2024/6/12
期刊
Journal of Cardiovascular Computed Tomography
出版商
Elsevier
简介
Background
Pre-eclampsia is a pregnancy related disorder associated with hypertension and vascular inflammation, factors that are also involved in the pathological pathway of aortic dilatation and aneurysm development. It is, however, unknown if younger women with previous pre-eclampsia have increased aortic dimensions. We tested the hypothesis that previous pre-eclampsia is associated with increased aortic dimensions in younger women.
Methods
The study was a cross-sectional cohort study of women with previous pre-eclampsia, aged 40–55, from the PRECIOUS population matched by age and parity with women from the general population. Using contrast-enhanced CT, aortic diameters were measured in the aortic root, ascending aorta, descending aorta, at the level of the diaphragm, suprarenal aorta, and infrarenal aorta.
Results
1355 women (684 with previous pre-eclampsia and 671 from the general …
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ELR Møller, MG Hauge, MHC Pham, P Damm… - Journal of Cardiovascular Computed Tomography, 2024