作者
Tenielle Porter, Samantha C Burnham, Lidija Milicic, Greg Savage, Paul Maruff, Yen Ying Lim, Qiao-Xin Li, David Ames, Colin L Masters, Stephanie Rainey-Smith, Christopher C Rowe, Olivier Salvado, David Groth, Giuseppe Verdile, Victor L Villemagne, Simon M Laws, AIBL Research Group
发表日期
2018/1/1
期刊
Journal of Alzheimer's Disease
卷号
66
期号
3
页码范围
1193-1211
出版商
IOS Press
简介
Background: With the exception of APOE, genetic variants associated with increased Alzheimer’s disease (AD) risk are characterized by small effect sizes. Polygenic risk scores (PRS) have shown utility in predicting AD risk; however, their utility for predicting decline in cognition at preclinical stages of AD is poorly understood.
学术搜索中的文章
T Porter, SC Burnham, L Milicic, G Savage, P Maruff… - Journal of Alzheimer's Disease, 2018