作者
SM Sajadi, Hossein Khoramdelazad, Gholamhossein Hassanshahi, Houshang Rafatpanah, Javad Hosseini, Mehdi Mahmoodi, Mohammad Kazemi Arababadi, Reza Derakhshan, Roshanak Hasheminasabzavareh, Seyed-Mostafa Hosseini-Zijoud, Zahra Ahmadi
发表日期
2013/1/1
期刊
Clin Lab
卷号
59
期号
1-2
页码范围
133-7
简介
Background: Recent evidence has demonstrated that environment and genetic factors play pivotal roles in diabe-tes and its related complications. The significant contributory role of cytokines in pathogenesis of type 2 diabetes is also well documented. This study was aimed to examine and compare both CXCL1 (GRO-α) and CXCL10 (IP-10) circulating levels in type 2 diabetic patients and healthy controls.
Methods: Peripheral blood samples were collected from 100 type 2 diabetic patients and 150 healthy controls. Cir-culating CXCL1 and CXCL10 levels were measured by ELISA.
Results: Elevated serum levels of both CXCL1 and CXCL10 were found in type 2 diabetic patients in comparison to controls.
Conclusions: Elevated levels of CXCL1 and CXCL10 could possibly be used as a marker of inflammation and an-giogenesis/angiostasis in type 2 diabetes.(Clin. Lab. 2013; 59: 133-137. DOI: 10.7754/Clin. Lab. 2012.120225)
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SM Sajadi, H Khoramdelazad, G Hassanshahi… - Clin Lab, 2013