作者
Rami Adel Pashameah, Atif Abdulwahab A Oyouni, Osama M Al-Amer, Waseem AlZamzami, Hussam AE Althagafi, Fahad Alharthi, P Vijayaraghavan, MA Rathi, VK Gopalakrishnan, V Duraipandiyan
发表日期
2022/11/1
期刊
Journal of King Saud University-Science
卷号
34
期号
8
页码范围
102361
出版商
Elsevier
简介
Background
Esophageal cancer has been reported in various countries, including Saudi Arabia, India and United States. Many biomarkers have been used to detect cancers at an early stage to improve the survival rate of esophageal cancer.
Methods
The present study investigated the biomarkers, biglycan, myeloperoxidase, cytokine (TNF-α, IFN-γ, IL-10 and IL-12) and carcinoembryonic antigen (CEA), squamous cell carcinoma antigen (SCC) and carbohydrate antigen L1 cell adhesion molecule from the tumour and non-tumour samples.
Results
The increased amount of circulatory biglycan level was detected using the ELISA method in tumour cases compared to control samples (p < 0.001). The expression of biglycan was high in certain tumour cases and was statistically significant (p < 0.01). The variation of myeloperoxidase markers in control and experimental subjects were statistically significant (p < 0.01 …
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RA Pashameah, AAA Oyouni, OM Al-Amer… - Journal of King Saud University-Science, 2022