作者
Cristina Ponte, Peter C Grayson, Joanna C Robson, Ravi Suppiah, Katherine Bates Gribbons, Andrew Judge, Anthea Craven, Sara Khalid, Andrew Hutchings, Richard A Watts, Peter A Merkel, Raashid A Luqmani
发表日期
2022/12/1
期刊
Annals of the Rheumatic Diseases
卷号
81
期号
12
页码范围
1647-1653
出版商
BMJ Publishing Group Ltd
简介
Objective
To develop and validate updated classification criteria for giant cell arteritis (GCA).
Methods
Patients with vasculitis or comparator diseases were recruited into an international cohort. The study proceeded in six phases: (1) identification of candidate items, (2) prospective collection of candidate items present at the time of diagnosis, (3) expert panel review of cases, (4) data‐driven reduction of candidate items, (5) derivation of a points‐based risk classification score in a development data set and (6) validation in an independent data set.
Results
The development data set consisted of 518 cases of GCA and 536 comparators. The validation data set consisted of 238 cases of GCA and 213 comparators. Age ≥50 years at diagnosis was an absolute requirement for classification. The final criteria items and weights were as follows: positive temporal artery biopsy or temporal artery halo sign on ultrasound (+5 …
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