作者
Bernhard Paulweber, P Valensi, J Lindström, NM Lalic, CJ Greaves, M McKee, K Kissimova-Skarbek, S Liatis, E Cosson, J Szendroedi, KE Sheppard, K Charlesworth, A-M Felton, M Hall, Aila Rissanen, J Tuomilehto, PE Schwarz, M Roden, M Paulweber, A Stadlmayr, L Kedenko, N Katsilambros, K Makrilakis, Z Kamenov, P Evans, A Gilis-Januszewska, K Lalic, A Jotic, P Djordevic, V Dimitrijevic-Sreckovic, U Hühmer, B Kulzer, S Puhl, YH Lee-Barkey, A AlKerwi, Charles Abraham, W Hardeman, T Acosta, M Adler, N Barengo, R Barengo, JM Boavida, V Christov, B Claussen, X Cos, S Deceukelier, P Djordjevic, M Fischer, R Gabriel-Sanchez, M Goldfracht, JL Gomez, U Handke, H Hauner, J Herbst, N Hermanns, L Herrebrugh, C Huber, J Huttunen, S Karadeniz, M Khalangot, D Köhler, V Kopp, P Kronsbein, D Kyne-Grzebalski, R Landgraf, C McIntosh, AC Mesquita, D Misina, F Muylle, A Neumann, AC Paiva, P Pajunen, M Peltonen, L Perrenoud, A Pfeiffer, A Pölönen, F Raposo, T Reinehr, C Robinson, U Rothe, T Saaristo, J Scholl, S Spiers, T Stemper, B Stratmann, Z Szybinski, T Tankova, V Telle-Hjellset, G Terry, Daniel Tolks, F Toti, A Undeutsch, C Valadas, D Velickiene, P Vermunt, R Weiss, J Wens, T Yilmaz
发表日期
2010/4
期刊
Hormone and Metabolic research
卷号
42
期号
S 01
页码范围
S3-S36
出版商
© Georg Thieme Verlag KG Stuttgart· New York
简介
Background
The prevalence and socioeconomic burden of type 2 diabetes (T2DM) and associated co-morbidities are rising worldwide.
Aims
This guideline provides evidence-based recommendations for preventing T2DM.
Methods
A European multidisciplinary consortium systematically reviewed the evidence on the effectiveness of screening and interventions for T2DM prevention using SIGN criteria.
Results
Obesity and sedentary lifestyle are the main modifiable risk factors. Age and ethnicity are non-modifiable risk factors. Case-finding should follow a step-wise procedure using risk questionnaires and oral glucose tolerance testing. Persons with impaired glucose tolerance and/or fasting glucose are at high-risk and should be prioritized for intensive intervention. Interventions supporting lifestyle changes delay the onset of T2DM in high-risk adults (number-needed-to-treat: 6.4 over 1.8–4.6 years). These should …
引用总数
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