作者
Maren S Fragala, Adam R Jajtner, Kyle S Beyer, Jeremy R Townsend, Nadia S Emerson, Tyler C Scanlon, Leonardo P Oliveira, Jay R Hoffman, Jeffrey R Stout
发表日期
2014/6
期刊
Journal of cachexia, sarcopenia and muscle
卷号
5
页码范围
139-148
出版商
Springer Berlin Heidelberg
简介
Background
N-terminal peptide of procollagen type III (P3NP) and C-terminal agrin fragment (CAF) are circulating biomarkers that are related to lean body mass in older adults. P3NP is a circulating marker reflective of muscular structural remodeling while CAF is a circulating marker of neuromuscular remodeling. As resistance exercise is an established intervention that can effectively improve muscle quality, we sought to evaluate circulating biomarker changes corresponding to a resistance exercise intervention in older adults.
Methods
Twenty-three older adults (aged 61 to 85 years) were randomized into an intervention (6-week resistance training) or control group. Resting circulating P3NP, CAF, lean body mass (LBM), muscle cross-sectional area (CSA), muscle strength, and muscle quality were determined at baseline and after the intervention or …
学术搜索中的文章
MS Fragala, AR Jajtner, KS Beyer, JR Townsend… - Journal of cachexia, sarcopenia and muscle, 2014