作者
Farzana Afroze, Monira Sarmin, CA Kawser, Sharika Nuzhat, Lubaba Shahrin, Haimanti Saha, Nusrat Jahan Shaly, Irin Parvin, Mohsena Bint-e Sharif, M Al Mamun, Tahmeed Ahmed, Mohammod Jobayer Chisti
发表日期
2021/3
来源
SAGE Open Medicine
卷号
9
页码范围
20503121211004825
出版商
SAGE Publications
简介
Objective
To determine the hypertonic saline efficacy in children with cerebral edema and raised intracranial pressure.
Method
Studies assessing the efficacy and safety of hypertonic saline in children with cerebral edema and elevated intracranial pressure were identified using Medline, Web of Science, Scopus, and Google Scholar databases. Two reviewers independently assessed papers for inclusion. The primary outcome was a reduction of elevated intracranial pressure by the administration of hypertonic saline.
Results
We initially evaluated 1595 potentially relevant articles, and only 7 studies met the eligibility criteria for the final analysis. Out of the seven studies, three of them were randomized controlled trials. Three of the studies found that hypertonic saline significantly reduced elevated intracranial pressure compared to control. One study reported a resolution of the comatose state as a measure of reduced …
学术搜索中的文章
F Afroze, M Sarmin, CA Kawser, S Nuzhat, L Shahrin… - SAGE Open Medicine, 2021