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Lignans are large group of polyphenols that are formed by the coupling of two coniferyl alcohol residues. Based on their origin, lignans are broadly grouped into plant lignans such as isolariciresinol, secoisolariciresinol diglucoside, lariciresinol, and matairesinol; and mammalian lignans such as enterodiol and enterolactone. Based on the oxidation level of the lignan skeleton, they are also categorized into numerous groups such as dibenzylfuran, dibenzylbutyrolactol, dihydroxybenzylbutane, arylnaphtalene and aryltetraline lactone derivatives. Depending on structural type and concentration, numerous dietary lignans have been shown to possess biological activities including protective effect against diseases such as hormone-dependent tumors and cardiovascular diseases. Also, they display antioxidant properties in tissues and organs including the liver and the brain, lignans are found in most fiber …