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Increased vitamin D intake may preserve or increase bone mineral density (BMD) in older persons.

A 2-y double-blind study was undertaken to determine whether weekly administration of 10 000 units of vitamin D₂ maintained or increased BMD in younger postmenopausal women more efficiently than did calcium supplements alone.

One hundred eighty-seven women who were ≥ 1 y postmenopausal were randomly assigned to take either 1000 mg Ca/d after the evening meal or 1000 mg Ca/d plus 10 000 U vitamin D₂/wk in a double-blind, placebo-controlled format. The BMD of the proximal forearm, lumbar spine, femoral neck, Ward’s triangle, and femoral trochanter was measured at 6-mo intervals by osteodensitometry.

During the 2-y period, there was no significant difference in the change in BMD at any site between the subjects taking calcium supplements and those taking …