作者
Anna A Pendina, Olga A Efimova, Olga G Chiryaeva, Andrei V Tikhonov, Petrova Lubov’I, Vera S Dudkina, Natalia A Sadik, Irina D Fedorova, Ilona A Galembo, Tatyana V Kuznetzova, Alexander M Gzgzyan, Vladislav S Baranov
发表日期
2014/2/1
期刊
Journal of assisted reproduction and genetics
卷号
31
期号
2
页码范围
149-155
出版商
Springer US
简介
Purpose
To compare the frequency and the spectrum of karyotype abnormality in the first trimester miscarriages in women aged under and over 35 years, who conceived naturally (NC) and who conceived through in vitro fertilization (IVF).
Methods
Comparative analysis of cytogenetic data obtained by karyotyping of miscarriages in patients who conceived naturally, and who conceived through IVF. Patients were subcategorized by their age: <35 years (NC, n = 173; IVF, n = 108) and ≥35 years (NC, n = 107; IVF, n = 111).
Results
A total of 499 miscarriage karyotypes was analyzed. The spectrum and the relative proportions of different cytogenetic categories in karyotypically abnormal miscarriages differed neither between the NC and IVF patients aged <35 years, nor between the NC and IVF patients aged ≥35 …
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