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Objective:

To evaluate the acquisition rate, identify risk factors, and estimate the risk for subsequent infection, associated with the colonization of the digestive tract with extended-spectrum beta-lactamase–producing Enterobacteriaceae during ICU-hospitalization.

Data Sources:

PubMed, EMBASE, and reference lists of all eligible articles.

Study Selection:

Included studies provided data on ICU-acquired colonization with extended-spectrum beta-lactamase–producing Enterobacteriaceae in previously noncolonized and noninfected patients and used the double disk synergy test for extended-spectrum beta-lactamase–producing Enterobacteriaceae phenotypic confirmation. Studies reporting extended-spectrum beta-lactamase–producing Enterobacteriaceae outbreaks or data on pediatric population were excluded.

Data Extraction:

Two authors independently assessed study eligibility and performed data extraction.

Data …