作者
Tomas Konecny, Amber D Khanna, Jan Novak, Abdi A Jama, George M Zawadowski, Marek Orban, Gregg Pressman, Jan Bukartyk, Tomas Kara, Frank Cetta Jr, Barry A Borlaug, Virend K Somers, Guy S Reeder
发表日期
2014/12/1
期刊
Catheterization and Cardiovascular Interventions
卷号
84
期号
7
页码范围
1138-1145
简介
Objectives
We set to measure the interatrial pressure gradient during simulated obstructive sleep apnea (OSA).
Background
OSA occurs when a sleeping patient attempts to inhale against an obstructed airway. How this event affects the interatrial pressure gradient has not been defined. We hypothesized that simulated OSA in a conscious subject (Mueller maneuver [MM], inspiration against obstruction) would promote increased right‐to‐left pressure gradient, and then the substrate for right‐to‐left atrial shunting.
Methods
Selected patients underwent simultaneous measurement of airway and atrial pressures (both left and right atrium [LA, RA]) using high‐fidelity micromanometry at rest, during MM, and during VM, during right heart catheterization.
Results
Ten patients (age 55 ± 11 years, two women) were successfully studied. During the onset of MM, RA pressure transiently but consistently exceeded LA …
学术搜索中的文章
T Konecny, AD Khanna, J Novak, AA Jama… - Catheterization and Cardiovascular Interventions, 2014