作者
Charles Agyemang, Erik Beune, Karlijn Meeks, Ellis Owusu-Dabo, Peter Agyei-Baffour, Ama de-Graft Aikins, Francis Dodoo, Liam Smeeth, Juliet Addo, Frank P Mockenhaupt, Stephen K Amoah, Matthias B Schulze, Ina Danquah, Joachim Spranger, Mary Nicolaou, Kerstin Klipstein-Grobusch, Tom Burr, Peter Henneman, Marcel M Mannens, Jan P Van Straalen, Silver Bahendeka, AH Zwinderman, Anton E Kunst, Karien Stronks
发表日期
2015/1/1
期刊
BMJ open
卷号
4
期号
3
页码范围
e004877
出版商
British Medical Journal Publishing Group
简介
Introduction
Obesity and type 2 diabetes (T2D) are highly prevalent among African migrants compared with European descent populations. The underlying reasons still remain a puzzle. Gene–environmental interaction is now seen as a potential plausible factor contributing to the high prevalence of obesity and T2D, but has not yet been investigated. The overall aim of the Research on Obesity and Diabetes among African Migrants (RODAM) project is to understand the reasons for the high prevalence of obesity and T2D among sub-Saharan Africans in diaspora by (1) studying the complex interplay between environment (eg, lifestyle), healthcare, biochemical and (epi)genetic factors, and their relative contributions to the high prevalence of obesity and T2D; (2) to identify specific risk factors within these broad categories to guide intervention programmes and (3) to provide a basic knowledge for improving diagnosis …
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C Agyemang, E Beune, K Meeks, E Owusu-Dabo… - BMJ open, 2015