Revisiting an old riddle: what determines genetic diversity levels within species? EM Leffler, K Bullaughey, DR Matute, WK Meyer, L Ségurel, A Venkat, ... Public Library of Science 10 (9), e1001388, 2012 | 599 | 2012 |
A fine-scale chimpanzee genetic map from population sequencing A Auton, A Fledel-Alon, S Pfeifer, O Venn, L Ségurel, T Street, EM Leffler, ... science 336 (6078), 193-198, 2012 | 323 | 2012 |
Stable recombination hotspots in birds S Singhal, EM Leffler, K Sannareddy, I Turner, O Venn, DM Hooper, ... Science 350 (6263), 928-932, 2015 | 319 | 2015 |
Multiple instances of ancient balancing selection shared between humans and chimpanzees EM Leffler, Z Gao, S Pfeifer, L Ségurel, A Auton, O Venn, R Bowden, ... Science 339 (6127), 1578-1582, 2013 | 319 | 2013 |
A novel locus of resistance to severe malaria in a region of ancient balancing selection MGE Network Nature 526, 253–257, 2015 | 208 | 2015 |
Resistance to malaria through structural variation of red blood cell invasion receptors EM Leffler, G Band, GBJ Busby, K Kivinen, QS Le, GM Clarke, KA Bojang, ... Science 356 (6343), eaam6393, 2017 | 180 | 2017 |
Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania Nature communications 10 (1), 5732, 2019 | 143 | 2019 |
Variation in human recombination rates and its genetic determinants A Fledel-Alon, EM Leffler, Y Guan, M Stephens, G Coop, M Przeworski PloS one 6 (6), e20321, 2011 | 123 | 2011 |
Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study CM Ndila, S Uyoga, AW Macharia, G Nyutu, N Peshu, J Ojal, M Shebe, ... The Lancet Haematology 5 (8), e333-e345, 2018 | 108 | 2018 |
The case of the fickle fingers: how the PRDM9 zinc finger protein specifies meiotic recombination hotspots in humans L Ségurel, EM Leffler, M Przeworski PLoS biology 9 (12), e1001211, 2011 | 100 | 2011 |
Malaria protection due to sickle haemoglobin depends on parasite genotype G Band, EM Leffler, M Jallow, F Sisay-Joof, CM Ndila, AW Macharia, ... Nature 602 (7895), 106-111, 2022 | 44 | 2022 |
Inferring adaptive gene-flow in recent African history G Busby, R Christ, G Band, E Leffler, QS Le, K Rockett, D Kwiatkowski, ... BioRxiv, 205252, 2017 | 16 | 2017 |
Evolutionary insights from wild vervet genomes EM Leffler Nature genetics 49 (12), 1671-1672, 2017 | 4 | 2017 |
The protective effect of sickle cell haemoglobin against severe malaria depends on parasite genotype G Band, EM Leffler, M Jallow, F Sisay-Joof, CM Ndila, AW Macharia, ... bioRxiv, 2021.03. 30.437659, 2021 | 3 | 2021 |
High-throughput genotyping assays for identification of glycophorin B deletion variants in population studies DSY Amuzu, KA Rockett, EM Leffler, F Ansah, N Amoako, CM Morang’a, ... Experimental Biology and Medicine 246 (8), 916-928, 2021 | 2 | 2021 |
Rapid Evolution of Glycan Recognition Receptors Reveals an Axis of Host–Microbe Arms Races beyond Canonical Protein–Protein Interfaces ZA Hilbert, PE Haffener, HJ Young, MJW Schwiesow, EM Leffler, NC Elde Genome Biology and Evolution 15 (7), evad119, 2023 | 1 | 2023 |
Characterization of Blood Group Variants in an Omani Population by Comparison of Whole Genome Sequencing and Serology PE Haffener, AZ Al Riyami, S Al-Zadjali, M Al-Rawahi, S Al Hosni, ... bioRxiv, 2024.06. 17.599396, 2024 | | 2024 |
Large-scale genotyping and meta-analysis of PIEZO1 short tandem repeat alleles suggest a modest association with malaria susceptibility EM Leffler, G Band, AE Jeffreys, K Rowlands, C Hubbart, KA Bojang, ... bioRxiv, 2024.06. 12.598682, 2024 | | 2024 |
Adaptive admixture at ACKR1 (the Duffy locus) may have shaped Plasmodium vivax prevalence in Oman PE Haffener, AZ Al-Riyami, S Al-Zadjali, GBJ Busby, S Al Mahdhuri, ... bioRxiv, 2024.03. 06.583766, 2024 | | 2024 |
IMPACT OF MALARIA-PROTECTIVE GLYCOPHORIN POLYMORPHISM ON PLASMODIUM FALCIPARUM INVASION S Kariuki, A Marin-Menendez, E Leffler, G Band, K Rockett, A Macharia, ... AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 99 (4), 26-26, 2018 | | 2018 |