Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate L Bunse, S Pusch, T Bunse, F Sahm, K Sanghvi, M Friedrich, D Alansary, ... Nature medicine 24 (8), 1192-1203, 2018 | 453 | 2018 |
Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis ND Mathewson, O Ashenberg, I Tirosh, S Gritsch, EM Perez, S Marx, ... Cell 184 (5), 1281-1298. e26, 2021 | 277 | 2021 |
Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas M Friedrich, R Sankowski, L Bunse, M Kilian, E Green, ... Nature cancer 2 (7), 723-740, 2021 | 154 | 2021 |
Preclinical characterization of AMG 330, a CD3/CD33-bispecific t-cell–engaging antibody with potential for treatment of acute myelogenous leukemia M Friedrich, A Henn, T Raum, M Bajtus, K Matthes, L Hendrich, J Wahl, ... Molecular cancer therapeutics 13 (6), 1549-1557, 2014 | 154 | 2014 |
Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas K Aslan, V Turco, J Blobner, JK Sonner, AR Liuzzi, NG Núñez, D De Feo, ... Nature communications 11 (1), 931, 2020 | 141 | 2020 |
Programmable protein delivery with a bacterial contractile injection system J Kreitz, MJ Friedrich, A Guru, B Lash, M Saito, RK Macrae, F Zhang Nature 616 (7956), 357-364, 2023 | 121 | 2023 |
A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals P Demetriou, E Abu-Shah, S Valvo, S McCuaig, V Mayya, A Kvalvaag, ... Nature immunology 21 (10), 1232-1243, 2020 | 92 | 2020 |
The pre-existing T cell landscape determines the response to bispecific T cell engagers in multiple myeloma patients MJ Friedrich, P Neri, N Kehl, J Michel, S Steiger, M Kilian, N Leblay, ... Cancer Cell 41 (April 10, 2023), 1-15, 2023 | 90 | 2023 |
Halsted’s “see one, do one, and teach one” versus Peyton’s four-step approach: a randomized trial for training of laparoscopic suturing and knot tying P Romero, P Günther, KF Kowalewski, M Friedrich, MW Schmidt, ... Journal of surgical education 75 (2), 510-515, 2018 | 73 | 2018 |
Evaluation of app-based serious gaming as a training method in teaching chest tube insertion to medical students: randomized controlled trial P Haubruck, F Nickel, J Ober, T Walker, C Bergdolt, M Friedrich, ... Journal of medical Internet research 20 (5), e195, 2018 | 63 | 2018 |
LapTrain: multi-modality training curriculum for laparoscopic cholecystectomy—results of a randomized controlled trial KF Kowalewski, CR Garrow, T Proctor, AA Preukschas, M Friedrich, ... Surgical endoscopy 32, 3830-3838, 2018 | 56 | 2018 |
Dysfunctional dendritic cells limit antigen-specific T cell response in glioma M Friedrich, M Hahn, J Michel, R Sankowski, M Kilian, N Kehl, M Günter, ... Neuro-oncology 25 (2), 263-276, 2023 | 49 | 2023 |
Ileus Management International (IMAGINE): protocol for a multicentre, observational study of ileus after colorectal surgery EuroSurg Collaborative, T Arthur, E Chan, I Fomin, D Ho, S Morgan, ... Colorectal Disease 20 (1), O17-O25, 2018 | 43 | 2018 |
Monitoring innate immune cell dynamics in the glioma microenvironment by magnetic resonance imaging and multiphoton microscopy (MR-MPM) K Karimian-Jazi, P Münch, A Alexander, M Fischer, K Pfleiderer, ... Theranostics 10 (4), 1873, 2020 | 40 | 2020 |
Tryptophan metabolism in brain tumors—IDO and beyond M Platten, M Friedrich, DA Wainwright, V Panitz, CA Opitz Current opinion in immunology 70, 57-66, 2021 | 36 | 2021 |
MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors M Kilian, R Sheinin, CL Tan, M Friedrich, C Krämer, A Kaminitz, ... Cancer Cell 41 (2), 235-251. e9, 2023 | 35 | 2023 |
Targeting of scavenger receptors stabilin-1 and stabilin-2 ameliorates atherosclerosis by a plasma proteome switch mediating monocyte/macrophage suppression CP Manta, T Leibing, M Friedrich, H Nolte, M Adrian, K Schledzewski, ... Circulation 146 (23), 1783-1799, 2022 | 32 | 2022 |
Perspectives of immunotherapy in isocitrate dehydrogenase-mutant gliomas M Friedrich, L Bunse, W Wick, M Platten Current opinion in oncology 30 (6), 368-374, 2018 | 24 | 2018 |
App-based serious gaming for training of chest tube insertion: study protocol for a randomized controlled trial M Friedrich, C Bergdolt, P Haubruck, T Bruckner, KF Kowalewski, ... Trials 18, 1-6, 2017 | 20 | 2017 |
Postoperative complications and mobilisation following major abdominal surgery with vs. without fitness tracker-based feedback (EXPELLIARMUS): study protocol for a student-led … M Schwab, N Brindl, A Studier-Fischer, T Tu, J Gsenger, M Pilgrim, ... Trials 21, 1-13, 2020 | 16 | 2020 |