Modulation of oxidative stress as an anticancer strategy C Gorrini, IS Harris, TW Mak Nature reviews Drug discovery 12 (12), 931-947, 2013 | 3435 | 2013 |
Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression IS Harris, AE Treloar, S Inoue, M Sasaki, C Gorrini, KC Lee, KY Yung, ... Cancer cell 27 (2), 211-222, 2015 | 957 | 2015 |
Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assembly M Ceci, C Gaviraghi, C Gorrini, LA Sala, N Offenhäuser, ... Nature 426 (6966), 579-584, 2003 | 512 | 2003 |
Glutathione primes T cell metabolism for inflammation TW Mak, M Grusdat, GS Duncan, C Dostert, Y Nonnenmacher, M Cox, ... Immunity 46 (4), 675-689, 2017 | 463 | 2017 |
Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress C Bassi, J Ho, T Srikumar, RJO Dowling, C Gorrini, SJ Miller, TW Mak, ... Science 341 (6144), 395-399, 2013 | 454 | 2013 |
Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response C Gorrini, M Squatrito, C Luise, N Syed, D Perna, L Wark, F Martinato, ... Nature 448 (7157), 1063-1067, 2007 | 387 | 2007 |
Tip60 in DNA damage response and growth control: many tricks in one HAT M Squatrito, C Gorrini, B Amati Trends in cell biology 16 (9), 433-442, 2006 | 357 | 2006 |
BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival C Gorrini, PS Baniasadi, IS Harris, J Silvester, S Inoue, B Snow, PA Joshi, ... Journal of Experimental Medicine 210 (8), 1529-1544, 2013 | 310 | 2013 |
E2F-Dependent Histone Acetylation and Recruitment of the Tip60 Acetyltransferase Complex to Chromatin in Late G1 S Taubert, C Gorrini, SR Frank, T Parisi, M Fuchs, HM Chan, ... Molecular and cellular biology 24 (10), 4546-4556, 2004 | 285 | 2004 |
Mutant IDH1 downregulates ATM and alters DNA repair and sensitivity to DNA damage independent of TET2 S Inoue, WY Li, A Tseng, I Beerman, AJ Elia, SC Bendall, F Lemonnier, ... Cancer cell 30 (2), 337-348, 2016 | 217 | 2016 |
Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1 C Roux, SM Jafari, R Shinde, G Duncan, DW Cescon, J Silvester, MF Chu, ... Proceedings of the National Academy of Sciences 116 (10), 4326-4335, 2019 | 160 | 2019 |
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15 S Inoue, Z Hao, AJ Elia, D Cescon, L Zhou, J Silvester, B Snow, IS Harris, ... Genes & development 27 (10), 1101-1114, 2013 | 152 | 2013 |
Estrogen controls the survival of BRCA1-deficient cells via a PI3K–NRF2-regulated pathway C Gorrini, BP Gang, C Bassi, A Wakeham, SP Baniasadi, Z Hao, WY Li, ... Proceedings of the National Academy of Sciences 111 (12), 4472-4477, 2014 | 137 | 2014 |
Role of Nek2 on centrosome duplication and aneuploidy in breast cancer cells P Cappello, H Blaser, C Gorrini, DCC Lin, AJ Elia, A Wakeham, S Haider, ... Oncogene 33 (18), 2375-2384, 2014 | 123 | 2014 |
AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer SP Kubli, C Bassi, C Roux, A Wakeham, C Göbl, W Zhou, SM Jafari, ... Proceedings of the National Academy of Sciences 116 (9), 3604-3613, 2019 | 105 | 2019 |
Assessing Associations between the AURKA-HMMR-TPX2-TUBG1 Functional Module and Breast Cancer Risk in BRCA1/2 Mutation Carriers I Blanco, K Kuchenbaecker, D Cuadras, X Wang, D Barrowdale, ... PLoS One 10 (4), e0120020, 2015 | 79 | 2015 |
The acetyltransferase Tip60 contributes to mammary tumorigenesis by modulating DNA repair C Bassi, YT Li, K Khu, F Mateo, PS Baniasadi, A Elia, J Mason, ... Cell Death & Differentiation 23 (7), 1198-1208, 2016 | 74 | 2016 |
The E3 ubiquitin ligase Mule acts through the ATM–p53 axis to maintain B lymphocyte homeostasis Z Hao, GS Duncan, YW Su, WY Li, J Silvester, C Hong, H You, D Brenner, ... Journal of Experimental Medicine 209 (1), 173-186, 2012 | 74 | 2012 |
Fibronectin controls cap-dependent translation through β1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathways C Gorrini, F Loreni, V Gandin, LA Sala, N Sonenberg, PC Marchisio, ... Proceedings of the National Academy of Sciences 102 (26), 9200-9205, 2005 | 52 | 2005 |
Effect of apoptogenic stimuli on colon carcinoma cell lines with a different c-myc expression level C Gorrini, M Donzelli, A Torriglia, R Supino, O Brison, R Bernardi, C Negri, ... International journal of molecular medicine 11 (6), 737-742, 2003 | 51 | 2003 |