Endothelial dysfunction in atherosclerotic cardiovascular diseases and beyond: from mechanism to pharmacotherapies S Xu, I Ilyas, PJ Little, H Li, D Kamato, X Zheng, S Luo, Z Li, P Liu, J Han, ... Pharmacological reviews 73 (3), 924-967, 2021 | 554 | 2021 |
Insulin resistance and atherosclerosis J Nigro, N Osman, AM Dart, PJ Little Endocrine reviews 27 (3), 242-259, 2006 | 448 | 2006 |
FOXO signaling pathways as therapeutic targets in cancer M Farhan, H Wang, U Gaur, PJ Little, J Xu, W Zheng International journal of biological sciences 13 (7), 815, 2017 | 410 | 2017 |
Cardiovascular actions and therapeutic potential of tanshinone IIA S Gao, Z Liu, H Li, PJ Little, P Liu, S Xu Atherosclerosis 220 (1), 3-10, 2012 | 381 | 2012 |
Transforming growth factor-β signalling: role and consequences of Smad linker region phosphorylation D Kamato, ML Burch, TJ Piva, HB Rezaei, MA Rostam, S Xu, W Zheng, ... Cellular signalling 25 (10), 2017-2024, 2013 | 317 | 2013 |
LOX-1 in atherosclerosis: biological functions and pharmacological modifiers S Xu, S Ogura, J Chen, PJ Little, J Moss, P Liu Cellular and Molecular Life Sciences 70, 2859-2872, 2013 | 306 | 2013 |
Cloning and expression of a rabbit cDNA encoding a serum-activated ethylisopropylamiloride-resistant epithelial Na+/H+ exchanger isoform (NHE-2) CM Tse, SA Levine, CH Yun, MH Montrose, PJ Little, J Pouyssegur, ... Journal of Biological Chemistry 268 (16), 11917-11924, 1993 | 279 | 1993 |
Zinc and cardiovascular disease PJ Little, R Bhattacharya, AE Moreyra, IL Korichneva Nutrition 26 (11-12), 1050-1057, 2010 | 263 | 2010 |
Effect of moderate alcohol upon obstructive sleep apnoea MF Scanlan, T Roebuck, PJ Little, MT Naughton European respiratory journal 16 (5), 909-913, 2000 | 263 | 2000 |
Proteoglycans synthesized by arterial smooth muscle cells in the presence of transforming growth factor-β1 exhibit increased binding to LDLs PJ Little, L Tannock, KL Olin, A Chait, TN Wight Arteriosclerosis, thrombosis, and vascular biology 22 (1), 55-60, 2002 | 204 | 2002 |
Endothelin-1 signalling in vascular smooth muscle: pathways controlling cellular functions associated with atherosclerosis ME Ivey, N Osman, PJ Little Atherosclerosis 199 (2), 237-247, 2008 | 176 | 2008 |
Targeting mechanosensitive transcription factors in atherosclerosis N Niu, S Xu, Y Xu, PJ Little, ZG Jin Trends in pharmacological sciences 40 (4), 253-266, 2019 | 154 | 2019 |
The possible role of the Akt signaling pathway in schizophrenia W Zheng, H Wang, Z Zeng, J Lin, PJ Little, LK Srivastava, R Quirion Brain research 1470, 145-158, 2012 | 152 | 2012 |
Naringenin and naringin in cardiovascular disease prevention: A preclinical review RH Moghaddam, Z Samimi, SZ Moradi, PJ Little, S Xu, MH Farzaei European Journal of Pharmacology 887, 173535, 2020 | 145 | 2020 |
Impact of sleep apnea on sympathetic nervous system activity in heart failure P Solin, DM Kaye, PJ Little, P Bergin, M Richardson, MT Naughton Chest 123 (4), 1119-1126, 2003 | 138 | 2003 |
Structure, function, pharmacology, and therapeutic potential of the G protein, Gα/q, 11 D Kamato, L Thach, R Bernard, V Chan, W Zheng, H Kaur, M Brimble, ... Frontiers in Cardiovascular Medicine 2, 129046, 2015 | 137 | 2015 |
Inhibitory activity of clinical thiazolidinedione peroxisome proliferator activating receptor-γ ligands toward internal mammary artery, radial artery, and saphenous vein smooth … ST de Dios, D Bruemmer, RJ Dilley, ME Ivey, GLR Jennings, RE Law, ... Circulation 107 (20), 2548-2550, 2003 | 128 | 2003 |
Targeting epigenetics and non-coding RNAs in atherosclerosis: from mechanisms to therapeutics S Xu, D Kamato, PJ Little, S Nakagawa, J Pelisek, ZG Jin Pharmacology & therapeutics 196, 15-43, 2019 | 124 | 2019 |
GLP-1 receptor agonists (GLP-1RAs): cardiovascular actions and therapeutic potential X Ma, Z Liu, I Ilyas, PJ Little, D Kamato, A Sahebka, Z Chen, S Luo, ... International journal of biological sciences 17 (8), 2050, 2021 | 121 | 2021 |
Endothelial function and dysfunction: Impact of metformin A Nafisa, SG Gray, Y Cao, T Wang, S Xu, FH Wattoo, M Barras, N Cohen, ... Pharmacology & therapeutics 192, 150-162, 2018 | 117 | 2018 |