关注
Jamie J. Manning, PhD
Jamie J. Manning, PhD
在 nyspi.columbia.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Do toxic synthetic cannabinoid receptor agonists have signature in vitro activity profiles? A case study of AMB-FUBINACA
DB Finlay*, JJ Manning*, MS Ibsen, CE Macdonald, M Patel, JA Javitch, ...
ACS chemical neuroscience 10 (10), 4350-4360, 2019
532019
Signalling profiles of a structurally diverse panel of synthetic cannabinoid receptor agonists
M Patel, JJ Manning, DB Finlay, JA Javitch, SD Banister, NL Grimsey, ...
Biochemical Pharmacology 175, 113871, 2020
512020
CUMYL-4CN-BINACA is an efficacious and potent pro-convulsant synthetic cannabinoid receptor agonist
RC Kevin, L Anderson, IS McGregor, R Boyd, JJ Manning, M Glass, ...
Frontiers in Pharmacology 10, 595, 2019
372019
Pharmacological selection of cannabinoid receptor effectors: Signalling, allosteric modulation and bias
JJ Manning, HM Green, M Glass, DB Finlay
Neuropharmacology 193, 108611, 2021
302021
Development of selective, fluorescent cannabinoid type 2 receptor ligands based on a 1, 8-naphthyridin-2-(1 H)-one-3-carboxamide scaffold
AG Cooper, CRM Oyagawa, JJ Manning, S Singh, S Hook, NL Grimsey, ...
Medchemcomm 9 (12), 2055-2067, 2018
222018
The chemistry and pharmacology of putative synthetic cannabinoid receptor agonist (SCRA) new psychoactive substances (NPS) 5F‐PY‐PICA, 5F‐PY‐PINACA, and their analogs
SD Banister, RC Kevin, L Martin, A Adams, C Macdonald, JJ Manning, ...
Drug Testing and Analysis 11 (7), 976-989, 2019
202019
Exploring stereochemical and conformational requirements at cannabinoid receptors for synthetic cannabinoids related to SDB-006, 5F-SDB-006, CUMYL-PICA, and 5F-CUMYL-PICA
A Ametovski, C Macdonald, JJ Manning, SAS Haneef, M Santiago, ...
ACS Chemical Neuroscience 11 (21), 3672-3682, 2020
182020
Defining Steric Requirements at CB1 and CB2 Cannabinoid Receptors Using Synthetic Cannabinoid Receptor Agonists 5F-AB-PINACA, 5F-ADB-PINACA, PX-1 …
J Markham, E Sparkes, R Boyd, S Chen, JJ Manning, D Finlay, F Lai, ...
ACS Chemical Neuroscience 13 (8), 1281-1295, 2022
102022
Cannabinoid 1 (CB1) receptor arrestin subtype‐selectivity and phosphorylation dependence
JJ Manning, G Rawcliffe, DB Finlay, M Glass
British Journal of Pharmacology 180 (3), 369-382, 2023
92023
Putative Synthetic Cannabinoids MEPIRAPIM, 5F-BEPIRAPIM (NNL-2), and Their Analogues Are T-Type Calcium Channel (CaV3) Inhibitors
RC Kevin, S Mirlohi, JJ Manning, R Boyd, EA Cairns, A Ametovski, F Lai, ...
ACS Chemical Neuroscience 13 (9), 1395-1409, 2022
62022
A novel “activation switch” motif common to all aminergic receptors
KH Lee, JJ Manning, J Javitch, L Shi
Journal of Chemical Information and Modeling, 2023
52023
Promiscuous G-protein activation by the calcium-sensing receptor
H Zuo, J Park, A Frangaj, J Ye, G Lu, JJ Manning, WB Asher, Z Lu, GB Hu, ...
Nature, 2024
12024
Exploring the Requirements for Arrestin Translocation to the Cannabinoid Type-1 Receptor
JJ Manning
The University of Otago, 2022
12022
Positive allosteric modulation of the cannabinoid CB1 receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics
HM Green, JJ Manning, IR Greig, RA Ross, DB Finlay, M Glass
British Journal of Pharmacology, 2024
2024
GPCR kinase subtype requirements for arrestin-2 and-3 translocation to the cannabinoid CB1 receptor and the consequences on G protein signalling
JJ Manning, DB Finlay, M Glass
Biochemical pharmacology 224, 116190, 2024
2024
Methods for automating the analysis of live-cell single-molecule FRET data
J Meszaros, P Geggier, JJ Manning, WB Asher, JA Javitch
Frontiers in Cell and Developmental Biology 11, 1184077, 2023
2023
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