Combating osteoporosis and obesity with exercise: leveraging cell mechanosensitivity GM Pagnotti, M Styner, G Uzer, VS Patel, LE Wright, KK Ness, TA Guise, ... Nature Reviews Endocrinology 15 (6), 339-355, 2019 | 190 | 2019 |
Cell mechanosensitivity to extremely low magnitude signals is enabled by a LINCed nucleus G Uzer, WR Thompson, B Sen, Z Xie, SS Yen, S Miller, G Bas, M Styner, ... Stem Cells, 2015 | 161 | 2015 |
mTORC2 regulates mechanically induced cytoskeletal reorganization and lineage selection in marrowderived mesenchymal stem cells B Sen, Z Xie, N Case, WR Thompson, G Uzer, M Styner, J Rubin Journal of Bone and Mineral Research 29 (1), 78-89, 2014 | 158 | 2014 |
Bone marrow fat accumulation accelerated by high fat diet is suppressed by exercise M Styner, WR Thompson, K Galior, G Uzer, X Wu, S Kadari, N Case, Z Xie, ... Bone 64, 39-46, 2014 | 151 | 2014 |
Intranuclear actin regulates osteogenesis B Sen, Z Xie, G Uzer, WR Thompson, M Styner, X Wu, J Rubin Stem cells 33 (10), 3065-3076, 2015 | 139 | 2015 |
Enucleated cells reveal differential roles of the nucleus in cell migration, polarity, and mechanotransduction DM Graham, T Andersen, L Sharek, G Uzer, K Rothenberg, BD Hoffman, ... Journal of Cell Biology 217 (3), 895-914, 2018 | 126 | 2018 |
Vibration induced osteogenic commitment of mesenchymal stem cells is enhanced by cytoskeletal remodeling but not fluid shear G Uzer, S Pongkitwitoon, M Ete Chan, S Judex Journal of Biomechanics 46 (13), 2296-2302, 2013 | 108 | 2013 |
Exercise decreases marrow adipose tissue through ßoxidation in obese running mice M Styner, GM Pagnotti, C McGrath, X Wu, B Sen, G Uzer, Z Xie, X Zong, ... Journal of Bone and Mineral Research 32 (8), 1692-1702, 2017 | 97 | 2017 |
Intranuclear actin structure modulates mesenchymal stem cell differentiation B Sen, G Uzer, RM Samsonraj, Z Xie, C McGrath, M Styner, A Dudakovic, ... Stem Cells 35 (6), 1624-1635, 2017 | 75 | 2017 |
The potential benefits and inherent risks of vibration as a non-drug therapy for the prevention and treatment of osteoporosis ME Chan, G Uzer, CT Rubin Current osteoporosis reports 11, 36-44, 2013 | 75 | 2013 |
Mechanically Activated Fyn Utilizes mTORC2 to Regulate RhoA and Adipogenesis in Mesenchymal Stem Cells WR Thompson, C Guilluy, Z Xie, B Sen, KE Brobst, SS Yen, G Uzer, ... Stem Cells 31 (11), 2528-2537, 2013 | 73 | 2013 |
Sun-mediated mechanical LINC between nucleus and cytoskeleton regulates βcatenin nuclear access G Uzer, G Bas, B Sen, Z Xie, S Birks, M Olcum, C McGrath, M Styner, ... Journal of biomechanics 74, 32-40, 2018 | 64 | 2018 |
Exercise regulation of marrow fat in the setting of PPARγ agonist treatment in female C57BL/6 mice M Styner, GM Pagnotti, K Galior, X Wu, WR Thompson, G Uzer, B Sen, ... Endocrinology 156 (8), 2753-2761, 2015 | 64 | 2015 |
Gap Junctional Communication in Osteocytes Is Amplified by Low Intensity Vibrations In Vitro G Uzer, S Pongkitwitoon, C Ian, WR Thompson, J Rubin, ME Chan, ... PloS ONE 9 (3), e90840, 2014 | 60 | 2014 |
Cell mechanosensitivity is enabled by the LINC nuclear complex G Uzer, CT Rubin, J Rubin Current molecular biology reports 2, 36-47, 2016 | 58 | 2016 |
Separating fluid shear stress from acceleration during vibrations in vitro: identification of mechanical signals modulating the cellular response G Uzer, SL Manske, ME Chan, FP Chiang, CT Rubin, MD Frame, S Judex Cellular and Molecular Bioengineering 5 (3), 266-276, 2012 | 57 | 2012 |
βcatenin preserves the stem state of murine bone marrow stromal cells through activation of EZH2 B Sen, CR Paradise, Z Xie, J Sankaran, G Uzer, M Styner, M Meyer, ... Journal of Bone and Mineral Research 35 (6), 1149-1162, 2020 | 54 | 2020 |
Exercise increases and browns muscle lipid in high-fat diet-fed mice TL Morton, K Galior, C McGrath, X Wu, G Uzer, GB Uzer, B Sen, Z Xie, ... Frontiers in endocrinology 7, 80, 2016 | 53 | 2016 |
Brief daily exposure to low-intensity vibration mitigates the degradation of the intervertebral disc in a frequency-specific manner N Holguin, G Uzer, FP Chiang, C Rubin, S Judex Journal of applied physiology 111 (6), 1846-1853, 2011 | 51 | 2011 |
Cytoskeletal configuration modulates mechanically induced changes in mesenchymal stem cell osteogenesis, morphology, and stiffness S Pongkitwitoon, G Uzer, J Rubin, S Judex Scientific reports 6 (1), 34791, 2016 | 50 | 2016 |