Genesis and growth of extracellular-vesicle-derived microcalcification in atherosclerotic plaques JD Hutcheson, C Goettsch, S Bertazzo, N Maldonado, JL Ruiz, W Goh, ... Nature materials 15 (3), 335-343, 2016 | 364 | 2016 |
Adventitial MSC-like cells are progenitors of vascular smooth muscle cells and drive vascular calcification in chronic kidney disease R Kramann, C Goettsch, J Wongboonsin, H Iwata, RK Schneider, ... Cell stem cell 19 (5), 628-642, 2016 | 308 | 2016 |
Serotonin receptors and heart valve disease—it was meant 2B JD Hutcheson, V Setola, BL Roth, WD Merryman Pharmacology & therapeutics 132 (2), 146-157, 2011 | 256 | 2011 |
Sortilin mediates vascular calcification via its recruitment into extracellular vesicles C Goettsch, JD Hutcheson, M Aikawa, H Iwata, T Pham, A Nykjaer, ... The Journal of clinical investigation 126 (4), 1323-1336, 2016 | 236 | 2016 |
Spatiotemporal multi-omics mapping generates a molecular atlas of the aortic valve and reveals networks driving disease F Schlotter, A Halu, S Goto, MC Blaser, SC Body, LH Lee, H Higashi, ... Circulation 138 (4), 377-393, 2018 | 218 | 2018 |
Valvular interstitial cells suppress calcification of valvular endothelial cells J Hjortnaes, K Shapero, C Goettsch, JD Hutcheson, J Keegan, J Kluin, ... Atherosclerosis 242 (1), 251-260, 2015 | 190 | 2015 |
Potential drug targets for calcific aortic valve disease JD Hutcheson, E Aikawa, WD Merryman Nature Reviews Cardiology 11 (4), 218-231, 2014 | 176 | 2014 |
Extracellular vesicles as mediators of cardiovascular calcification A Bakhshian Nik, JD Hutcheson, E Aikawa Frontiers in cardiovascular medicine 4, 78, 2017 | 140 | 2017 |
An electrically active microneedle array for electroporation SO Choi, YC Kim, JH Park, J Hutcheson, HS Gill, YK Yoon, MR Prausnitz, ... Biomedical microdevices 12, 263-273, 2010 | 138 | 2010 |
Small entities with large impact: microcalcifications and atherosclerotic plaque vulnerability JD Hutcheson, N Maldonado, E Aikawa Current opinion in lipidology 25 (5), 327-332, 2014 | 137 | 2014 |
A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification C Goettsch, JD Hutcheson, S Hagita, MA Rogers, MD Creager, T Pham, ... Atherosclerosis 251, 109-118, 2016 | 125 | 2016 |
Cadherin-11 regulates cell–cell tension necessary for calcific nodule formation by valvular myofibroblasts JD Hutcheson, J Chen, MK Sewell-Loftin, LM Ryzhova, CI Fisher, YR Su, ... Arteriosclerosis, thrombosis, and vascular biology 33 (1), 114-120, 2013 | 124 | 2013 |
MicroRNA in cardiovascular calcification: focus on targets and extracellular vesicle delivery mechanisms C Goettsch, JD Hutcheson, E Aikawa Circulation research 112 (7), 1073-1084, 2013 | 122 | 2013 |
5-HT2B antagonism arrests non-canonical TGF-β1-induced valvular myofibroblast differentiation JD Hutcheson, LM Ryzhova, V Setola, WD Merryman Journal of molecular and cellular cardiology 53 (5), 707-714, 2012 | 122 | 2012 |
Extracellular vesicles in cardiovascular calcification: expanding current paradigms JB Krohn, JD Hutcheson, E Martínez‐Martínez, E Aikawa The Journal of physiology 594 (11), 2895-2903, 2016 | 112 | 2016 |
18F-Fluoride Signal Amplification Identifies Microcalcifications Associated With Atherosclerotic Plaque Instability in Positron Emission Tomography/Computed … MD Creager, T Hohl, JD Hutcheson, AJ Moss, F Schlotter, MC Blaser, ... Circulation: Cardiovascular Imaging 12 (1), e007835, 2019 | 109 | 2019 |
Cardiovascular calcification: current controversies and novel concepts JL Ruiz, JD Hutcheson, E Aikawa Cardiovascular Pathology 24 (4), 207-212, 2015 | 106 | 2015 |
Dynamin-related protein 1 inhibition attenuates cardiovascular calcification in the presence of oxidative stress MA Rogers, N Maldonado, JD Hutcheson, C Goettsch, S Goto, I Yamada, ... Circulation research 121 (3), 220-233, 2017 | 99 | 2017 |
Directing valvular interstitial cell myofibroblast‐like differentiation in a hybrid hydrogel platform J Hjortnaes, G Camci‐Unal, JD Hutcheson, SM Jung, FJ Schoen, J Kluin, ... Advanced healthcare materials 4 (1), 121-130, 2015 | 95 | 2015 |
Simulation of early calcific aortic valve disease in a 3D platform: a role for myofibroblast differentiation J Hjortnaes, C Goettsch, JD Hutcheson, G Camci-Unal, L Lax, K Scherer, ... Journal of molecular and cellular cardiology 94, 13-20, 2016 | 87 | 2016 |