| A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants LG Fritsche, W Igl, JNC Bailey, F Grassmann, S Sengupta, ... Nature genetics 48 (2), 134-143, 2016 | 1439 | 2016 |
| A deep learning algorithm for prediction of age-related eye disease study severity scale for age-related macular degeneration from color fundus photography F Grassmann, J Mengelkamp, C Brandl, S Harsch, ME Zimmermann, ... Ophthalmology 125 (9), 1410-1420, 2018 | 493 | 2018 |
| Complement C3 inhibitor pegcetacoplan for geographic atrophy secondary to age-related macular degeneration: a randomized phase 2 trial DS Liao, FV Grossi, D El Mehdi, MR Gerber, DM Brown, JS Heier, ... Ophthalmology 127 (2), 186-195, 2020 | 433 | 2020 |
| Identification of a rare coding variant in complement 3 associated with age-related macular degeneration X Zhan, DE Larson, C Wang, DC Koboldt, YV Sergeev, RS Fulton, ... Nature genetics 45 (11), 1375-1379, 2013 | 192 | 2013 |
| Deep-intronic ABCA4 variants explain missing heritability in Stargardt disease and allow correction of splice defects by antisense oligonucleotides R Sangermano, A Garanto, M Khan, EH Runhart, M Bauwens, NM Bax, ... Genetics in Medicine 21 (8), 1751-1760, 2019 | 174 | 2019 |
| Mutation spectrum of the ABCA4 gene in 335 Stargardt disease patients from a multicenter German cohort—impact of selected deep intronic variants and common SNPs HL Schulz, F Grassmann, U Kellner, G Spital, K Rüther, H Jägle, ... Investigative ophthalmology & visual science 58 (1), 394-403, 2017 | 128 | 2017 |
| In-depth characterisation of Retinal Pigment Epithelium (RPE) cells derived from human induced pluripotent stem cells (hiPSC) C Brandl, SJ Zimmermann, VM Milenkovic, SMG Rosendahl, ... Neuromolecular medicine 16, 551-564, 2014 | 115 | 2014 |
| An eye on age-related macular degeneration: the role of microRNAs in disease pathology P Berber, F Grassmann, C Kiel, BHF Weber Molecular diagnosis & therapy 21, 31-43, 2017 | 105 | 2017 |
| Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator S Micklisch, Y Lin, S Jacob, M Karlstetter, K Dannhausen, P Dasari, ... Journal of neuroinflammation 14, 1-15, 2017 | 104 | 2017 |
| Modelling the genetic risk in age-related macular degeneration F Grassmann, LG Fritsche, CN Keilhauer, IM Heid, BHF Weber PLoS One 7 (5), e37979, 2012 | 99 | 2012 |
| Cell-type-specific complement expression in the healthy and diseased retina D Pauly, D Agarwal, N Dana, N Schäfer, J Biber, KA Wunderlich, Y Jabri, ... Cell reports 29 (9), 2835-2848. e4, 2019 | 84 | 2019 |
| A circulating microrna profile is associated with late-stage neovascular age-related macular degeneration F Grassmann, PGA Schoenberger, C Brandl, T Schick, D Hasler, ... PloS one 9 (9), e107461, 2014 | 82 | 2014 |
| The role of the complement system in age-related macular degeneration BHF Weber, PC Issa, D Pauly, P Herrmann, F Grassmann, FG Holz Deutsches Ärzteblatt International 111 (8), 133, 2014 | 82 | 2014 |
| Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease TW Winkler, F Grassmann, C Brandl, C Kiel, F Günther, T Strunz, ... BMC medical genomics 13, 1-18, 2020 | 77 | 2020 |
| Clinical and genetic factors associated with progression of geographic atrophy lesions in age-related macular degeneration F Grassmann, M Fleckenstein, EY Chew, T Strunz, ... PLoS One 10 (5), e0126636, 2015 | 75 | 2015 |
| Recombinant haplotypes narrow the ARMS2/HTRA1 association signal for age-related macular degeneration F Grassmann, IM Heid, BHF Weber, ... Genetics 205 (2), 919-924, 2017 | 73 | 2017 |
| A mega-analysis of expression quantitative trait loci (eQTL) provides insight into the regulatory architecture of gene expression variation in liver T Strunz, F Grassmann, J Gayán, S Nahkuri, D Souza-Costa, C Maugeais, ... Scientific reports 8 (1), 5865, 2018 | 65 | 2018 |
| Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration R Ratnapriya, X Zhan, RN Fariss, KE Branham, D Zipprer, CF Chakarova, ... Human molecular genetics 23 (21), 5827-5837, 2014 | 64 | 2014 |
| Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits F Grassmann, C Kiel, ME Zimmermann, M Gorski, V Grassmann, K Stark, ... Genome medicine 9, 1-13, 2017 | 63 | 2017 |
| The retinitis pigmentosa 28 protein FAM161A is a novel ciliary protein involved in intermolecular protein interaction and microtubule association F Zach, F Grassmann, T Langmann, N Sorusch, U Wolfrum, H Stöhr Human molecular genetics 21 (21), 4573-4586, 2012 | 59 | 2012 |
