| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13104* | 2021 |
| Discovery of potent VEGFR-2 inhibitors based on furopyrimidine and thienopyrimidne scaffolds as cancer targeting agents MA Aziz, RAT Serya, DS Lasheen, AK Abdel-Aziz, A Esmat, AM Mansour, ... Scientific reports 6 (1), 24460, 2016 | 148 | 2016 |
| Astaxanthin ameliorates doxorubicin-induced cognitive impairment (chemobrain) in experimental rat model: impact on oxidative, inflammatory, and apoptotic machineries SE El-Agamy, AK Abdel-Aziz, S Wahdan, A Esmat, SS Azab Molecular neurobiology 55, 5727-5740, 2018 | 143 | 2018 |
| Chloroquine synergizes sunitinib cytotoxicity via modulating autophagic, apoptotic and angiogenic machineries AK Abdel-Aziz, S Shouman, E El-Demerdash, M Elgendy, AB Abdel-Naim Chemico-biological interactions 217, 28-40, 2014 | 98 | 2014 |
| Chemotherapy and cognition: comprehensive review on doxorubicin-induced chemobrain SE El-Agamy, AK Abdel-Aziz, A Esmat, SS Azab Cancer chemotherapy and pharmacology 84, 1-14, 2019 | 77 | 2019 |
| Beclin 1 restrains tumorigenesis through Mcl-1 destabilization in an autophagy-independent reciprocal manner M Elgendy, M Ciro, AK Abdel-Aziz, G Belmonte, RD Zuffo, C Mercurio, ... Nature communications 5 (1), 5637, 2014 | 76 | 2014 |
| Mechanistic approach of the inhibitory effect of chrysin on inflammatory and apoptotic events implicated in radiation-induced premature ovarian failure: emphasis on TGF-β/MAPKs … EM Mantawy, RS Said, AK Abdel-Aziz Biomedicine & Pharmacotherapy 109, 293-303, 2019 | 52 | 2019 |
| Dual modulation of MCL-1 and mTOR determines the response to sunitinib M Elgendy, AK Abdel-Aziz, SL Renne, V Bornaghi, G Procopio, ... The Journal of clinical investigation 127 (1), 153-168, 2017 | 52 | 2017 |
| Surmounting the resistance against EGFR inhibitors through the development of thieno [2, 3-d] pyrimidine-based dual EGFR/HER2 inhibitors SN Milik, AK Abdel-Aziz, DS Lasheen, RAT Serya, S Minucci, ... European Journal of Medicinal Chemistry 155, 316-336, 2018 | 50 | 2018 |
| The tyrosine kinase inhibitor, sunitinib malate, induces cognitive impairment in vivo via dysregulating VEGFR signaling, apoptotic and autophagic machineries AK Abdel-Aziz, EM Mantawy, RS Said, R Helwa Experimental neurology 283, 129-141, 2016 | 48 | 2016 |
| Dendritic cell vaccine immunotherapy; the beginning of the end of cancer and COVID-19. A hypothesis MK Saadeldin, AK Abdel-Aziz, A Abdellatif Medical hypotheses 146, 110365, 2021 | 43 | 2021 |
| Serum sclerostin and irisin as predictive markers for atherosclerosis in Egyptian type II diabetic female patients: A case control study MK Saadeldin, SS Elshaer, IA Emara, M Maged, AK Abdel-Aziz PLoS One 13 (11), e0206761, 2018 | 39 | 2018 |
| Rational design, synthesis and molecular modeling studies of novel anti-oncological alkaloids against melanoma AS Girgis, SS Panda, AM Srour, H Farag, NSM Ismail, M Elgendy, ... Organic & Biomolecular Chemistry 13 (23), 6619-6633, 2015 | 35 | 2015 |
| Modulation of imatinib cytotoxicity by selenite in HCT 116 colorectal cancer cells AK AbdelAziz, SSE Azab, SS Youssef, AM ElSayed, E ElDemerdash, ... Basic & clinical pharmacology & toxicology 116 (1), 37-46, 2015 | 29 | 2015 |
| Tuning mTORC1 activity dictates the response of acute myeloid leukemia to LSD1 inhibition AK Abdel-Aziz, I Pallavicini, E Ceccacci, G Meroni, MK Saadeldin, ... haematologica 105 (8), 2105, 2020 | 28* | 2020 |
| Comparative study of anti-VEGF Ranibizumab and Interleukin-6 receptor antagonist Tocilizumab in Adjuvant-induced Arthritis AES Abdel-Maged, AM Gad, AK Abdel-Aziz, MM Aboulwafa, SS Azab Toxicology and Applied Pharmacology 356, 65-75, 2018 | 28 | 2018 |
| From resistance to sensitivity: insights and implications of biphasic modulation of autophagy by sunitinib AK Abdel-Aziz, AB Abdel-Naim, S Shouman, S Minucci, M Elgendy Frontiers in Pharmacology 8, 718, 2017 | 27 | 2017 |
| Chloroquine as a promising adjuvant chemotherapy together with sunitinib AK Abdel-Aziz, S Shouman, E El-Demerdash, M Elgendy, AB Abdel-Naim strategies 12, 15, 2014 | 15 | 2014 |
| Discovery of a benzimidazole-based dual FLT3/TrKA inhibitor targeting acute myeloid leukemia EME Dokla, AK Abdel-Aziz, SN Milik, MJ McPhillie, S Minucci, ... Bioorganic & Medicinal Chemistry 56, 116596, 2022 | 12 | 2022 |
| A critical review of chloroquine and hydroxychloroquine as potential adjuvant agents for treating people with cancer AK Abdel-Aziz, MK Saadeldin, AH Salem, SA Ibrahim, S Shouman, ... Future Pharmacology 2 (4), 431-443, 2022 | 9 | 2022 |
