Serine catabolism regulates mitochondrial redox control during hypoxia J Ye, J Fan, S Venneti, YW Wan, BR Pawel, J Zhang, LWS Finley, C Lu, ... Cancer discovery 4 (12), 1406-1417, 2014 | 438 | 2014 |
A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases S Yamamoto, M Jaiswal, WL Charng, T Gambin, E Karaca, G Mirzaa, ... Cell 159 (1), 200-214, 2014 | 405 | 2014 |
Complement C3aR inactivation attenuates tau pathology and reverses an immune network deregulated in tauopathy models and Alzheimer’s disease A Litvinchuk, YW Wan, DB Swartzlander, F Chen, A Cole, NE Propson, ... Neuron 100 (6), 1337-1353. e5, 2018 | 365 | 2018 |
Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease ER Roy, B Wang, Y Wan, G Chiu, A Cole, Z Yin, NE Propson, Y Xu, ... The Journal of clinical investigation 130 (4), 1912-1930, 2020 | 340 | 2020 |
Digital sorting of complex tissues for cell type-specific gene expression profiles Y Zhong, YW Wan, K Pang, LML Chow, Z Liu BMC bioinformatics 14, 1-10, 2013 | 229 | 2013 |
Meta-analysis of the Alzheimer’s disease human brain transcriptome and functional dissection in mouse models YW Wan, R Al-Ouran, CG Mangleburg, TM Perumal, TV Lee, K Allison, ... Cell reports 32 (2), 2020 | 215 | 2020 |
Reversal of phenotypes in MECP2 duplication mice using genetic rescue or antisense oligonucleotides Y Sztainberg, H Chen, JW Swann, S Hao, B Tang, Z Wu, J Tang, YW Wan, ... Nature 528 (7580), 123-126, 2015 | 211 | 2015 |
TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading H Martini-Stoica, AL Cole, DB Swartzlander, F Chen, YW Wan, L Bajaj, ... Journal of Experimental Medicine 215 (9), 2355-2377, 2018 | 199 | 2018 |
MARRVEL: integration of human and model organism genetic resources to facilitate functional annotation of the human genome J Wang, R Al-Ouran, Y Hu, SY Kim, YW Wan, MF Wangler, S Yamamoto, ... The American Journal of Human Genetics 100 (6), 843-853, 2017 | 183 | 2017 |
Molecular profiling predicts meningioma recurrence and reveals loss of DREAM complex repression in aggressive tumors AJ Patel, YW Wan, R Al-Ouran, JP Revelli, MF Cardenas, M Oneissi, L Xi, ... Proceedings of the National Academy of Sciences 116 (43), 21715-21726, 2019 | 165 | 2019 |
The bone microenvironment invigorates metastatic seeds for further dissemination W Zhang, IL Bado, J Hu, YW Wan, L Wu, H Wang, Y Gao, HH Jeong, Z Xu, ... Cell 184 (9), 2471-2486. e20, 2021 | 153 | 2021 |
TCGA2STAT: simple TCGA data access for integrated statistical analysis in R YW Wan, GI Allen, Z Liu Bioinformatics 32 (6), 952-954, 2016 | 153 | 2016 |
Disruption of the ATXN1–CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans HC Lu, Q Tan, MWC Rousseaux, W Wang, JY Kim, R Richman, YW Wan, ... Nature genetics 49 (4), 527-536, 2017 | 135 | 2017 |
Confirmation of gene expression–based prediction of survival in non–small cell lung cancer NL Guo, YW Wan, K Tosun, H Lin, Z Msiska, DC Flynn, SC Remick, ... Clinical Cancer Research 14 (24), 8213-8220, 2008 | 121 | 2008 |
The microRNA-200 family targets multiple non-small cell lung cancer prognostic markers in H1299 cells and BEAS-2B cells M Pacurari, JB Addison, N Bondalapati, YW Wan, D Luo, Y Qian, ... International journal of oncology 43 (2), 548-560, 2013 | 110 | 2013 |
ATXN1-CIC complex is the primary driver of cerebellar pathology in spinocerebellar ataxia type 1 through a gain-of-function mechanism MWC Rousseaux, T Tschumperlin, HC Lu, EP Lackey, VV Bondar, ... Neuron 97 (6), 1235-1243. e5, 2018 | 108 | 2018 |
Extensive cryptic splicing upon loss of RBM17 and TDP43 in neurodegeneration models Q Tan, HK Yalamanchili, J Park, A De Maio, HC Lu, YW Wan, JJ White, ... Human molecular genetics 25 (23), 5083-5093, 2016 | 103 | 2016 |
Multiwalled carbon nanotube-induced gene signatures in the mouse lung: potential predictive value for human lung cancer risk and prognosis NL Guo, YW Wan, J Denvir, DW Porter, M Pacurari, MG Wolfarth, ... Journal of Toxicology and Environmental Health, Part A 75 (18), 1129-1153, 2012 | 89 | 2012 |
Transcriptional regulation by ATOH1 and its target SPDEF in the intestine YH Lo, E Chung, Z Li, YW Wan, MM Mahe, MS Chen, TK Noah, KN Bell, ... Cellular and molecular gastroenterology and hepatology 3 (1), 51-71, 2017 | 83 | 2017 |
Molecular pathway identification using biological network-regularized logistic models W Zhang, Y Wan, GI Allen, K Pang, ML Anderson, Z Liu BMC genomics 14, 1-8, 2013 | 78 | 2013 |