Flavivirus NS4A-induced autophagy protects cells against death and enhances virus replication JE McLean, A Wudzinska, E Datan, D Quaglino, Z Zakeri Journal of Biological Chemistry 286 (25), 22147-22159, 2011 | 334 | 2011 |
Dengue-induced autophagy, virus replication and protection from cell death require ER stress (PERK) pathway activation E Datan, SG Roy, G Germain, N Zali, JE McLean, G Golshan, S Harbajan, ... Nature - Cell Death and Disease 7 (e2127), 1-10, 2016 | 141 | 2016 |
Lack of Bax prevents influenza A virus-induced apoptosis and causes diminished viral replication JE McLean, E Datan, D Matassov, ZF Zakeri Journal of virology 83 (16), 8233-8246, 2009 | 106 | 2009 |
Triptolide: reflections on two decades of research and prospects for the future L Tong, Q Zhao, E Datan, GQ Lin, I Minn, MG Pomper, B Yu, D Romo, ... Natural product reports 38 (4), 843-860, 2021 | 96 | 2021 |
mTOR/p70S6K signaling distinguishes routine, maintenance-level autophagy from autophagic cell death during influenza A infection E Datan, A Shirazian, S Benjamin, D Matassov, A Tinari, W Malorni, ... Virology 452, 175-190, 2014 | 89 | 2014 |
Targeted Delivery and Sustained Antitumor Activity of Triptolide through Glucose Conjugation (doi:10.1002/anie.201606121) QL He, I Minn, Q Wang, P Xu, SA Head, E Datan, B Yu, MG Pomper*, ... Angewandte Chemie International Edition 128, 1-6, 2016 | 75* | 2016 |
Regulation of cell survival and death during Flavivirus infections SG Roy, B Sadigh, E Datan, RA Lockshin, Z Zakeri World journal of biological chemistry 5 (2), 93, 2014 | 74 | 2014 |
Atorvastatin restricts the ability of influenza virus to generate lipid droplets and severely suppresses the replication of the virus D Episcopio, S Aminov, S Benjamin, G Germain, E Datan, J Landazuri, ... The FASEB Journal 33 (8), 9516, 2019 | 66 | 2019 |
HIF inhibitor 32-134D eradicates murine hepatocellular carcinoma in combination with anti-PD1 therapy S Salman, DJ Meyers, EE Wicks, SN Lee, E Datan, AM Thomas, ... Journal of Clinical Investigation 132 (9), 1-16, 2022 | 50 | 2022 |
NARF is a hypoxia-induced coactivator for OCT4-mediated breast cancer stem cell specification Y Yang, C Chen, Q Zuo, H Lu, S Salman, Y Lyu, TYT Huang, EE Wicks, ... Science Advances 8 (49), eabo5000, 2022 | 14 | 2022 |
A Glucose-Triptolide Conjugate Selectively Targets Cancer Cells Under Hypoxia E Datan, I Minn, P Xu, QL He, HH Ahn, B Yu, MG Pomper, JO Liu Cell Press - iScience, 101536, 2020 | 14 | 2020 |
Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis Q Zuo, Y Yang, Y Lyu, C Yang, C Chen, S Salman, TYT Huang, EE Wicks, ... Cell Reports 42 (3), 2023 | 6 | 2023 |
Autophagic cell death in viral infection: Do TAM receptors play a role? E Datan, S Salman International Review of Cell and Molecular Biology 357, 123-168, 2020 | 4 | 2020 |
Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes Y Lyu, Y Yang, V Talwar, H Lu, C Chen, S Salman, EE Wicks, TYT Huang, ... Cell Reports 43 (4), 2024 | 1 | 2024 |
Glucose triptolide conjugates and uses thereof JO Liu, E Datan, MG Pomper, I Minn, P Xu, B Yu US Patent App. 17/801,509, 2023 | | 2023 |
Mechanistic Studies of the Transcription Inhibitor Triptolide and its Selective Targeting to Cancer Cells under Hypoxia E Datan Johns Hopkins University, 2019 | | 2019 |
National Asian American and Pacific Islander Heritage Month - Feature Employee E Datan, JHMOD Inclusion https://www.linkedin.com/posts/emmanuel-datan-medicine_feature-article-back …, 2018 | | 2018 |
The NS4A Proteins from 4 Dengue Serotypes, Substantially Different in Sequence, Function Similarly to Induce Autophagy and Protect Mammalian Cells using ATM Pathways N Zali, SG Roy, E Datan, J McLean, L Alvarez, RA Lockshin, Z Zakeri | | 2018 |
Chapter 15: Cell death and virus infection - a short review. Z Zakeri, S Gosh-Roy, E Datan, J McLean, K Zandi, G Germain 20 Years of Cell Death (LINK is https://www.researchgate.net/publication …, 2015 | | 2015 |
WJBC SG Roy, B Sadigh, E Datan, RA Lockshin, Z Zakeri World 5 (2), 93-105, 2014 | | 2014 |