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Emmanuel Datan
Emmanuel Datan
Chemical Biologist/Pharmacologist at Johns Hopkins School of Medicine
在 jhmi.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Flavivirus NS4A-induced autophagy protects cells against death and enhances virus replication
JE McLean, A Wudzinska, E Datan, D Quaglino, Z Zakeri
Journal of Biological Chemistry 286 (25), 22147-22159, 2011
3342011
Dengue-induced autophagy, virus replication and protection from cell death require ER stress (PERK) pathway activation
E Datan, SG Roy, G Germain, N Zali, JE McLean, G Golshan, S Harbajan, ...
Nature - Cell Death and Disease 7 (e2127), 1-10, 2016
1412016
Lack of Bax prevents influenza A virus-induced apoptosis and causes diminished viral replication
JE McLean, E Datan, D Matassov, ZF Zakeri
Journal of virology 83 (16), 8233-8246, 2009
1062009
Triptolide: reflections on two decades of research and prospects for the future
L Tong, Q Zhao, E Datan, GQ Lin, I Minn, MG Pomper, B Yu, D Romo, ...
Natural product reports 38 (4), 843-860, 2021
962021
mTOR/p70S6K signaling distinguishes routine, maintenance-level autophagy from autophagic cell death during influenza A infection
E Datan, A Shirazian, S Benjamin, D Matassov, A Tinari, W Malorni, ...
Virology 452, 175-190, 2014
892014
Targeted Delivery and Sustained Antitumor Activity of Triptolide through Glucose Conjugation (doi:10.1002/anie.201606121)
QL He, I Minn, Q Wang, P Xu, SA Head, E Datan, B Yu, MG Pomper*, ...
Angewandte Chemie International Edition 128, 1-6, 2016
75*2016
Regulation of cell survival and death during Flavivirus infections
SG Roy, B Sadigh, E Datan, RA Lockshin, Z Zakeri
World journal of biological chemistry 5 (2), 93, 2014
742014
Atorvastatin restricts the ability of influenza virus to generate lipid droplets and severely suppresses the replication of the virus
D Episcopio, S Aminov, S Benjamin, G Germain, E Datan, J Landazuri, ...
The FASEB Journal 33 (8), 9516, 2019
662019
HIF inhibitor 32-134D eradicates murine hepatocellular carcinoma in combination with anti-PD1 therapy
S Salman, DJ Meyers, EE Wicks, SN Lee, E Datan, AM Thomas, ...
Journal of Clinical Investigation 132 (9), 1-16, 2022
502022
NARF is a hypoxia-induced coactivator for OCT4-mediated breast cancer stem cell specification
Y Yang, C Chen, Q Zuo, H Lu, S Salman, Y Lyu, TYT Huang, EE Wicks, ...
Science Advances 8 (49), eabo5000, 2022
142022
A Glucose-Triptolide Conjugate Selectively Targets Cancer Cells Under Hypoxia
E Datan, I Minn, P Xu, QL He, HH Ahn, B Yu, MG Pomper, JO Liu
Cell Press - iScience, 101536, 2020
142020
Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis
Q Zuo, Y Yang, Y Lyu, C Yang, C Chen, S Salman, TYT Huang, EE Wicks, ...
Cell Reports 42 (3), 2023
62023
Autophagic cell death in viral infection: Do TAM receptors play a role?
E Datan, S Salman
International Review of Cell and Molecular Biology 357, 123-168, 2020
42020
Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes
Y Lyu, Y Yang, V Talwar, H Lu, C Chen, S Salman, EE Wicks, TYT Huang, ...
Cell Reports 43 (4), 2024
12024
Glucose triptolide conjugates and uses thereof
JO Liu, E Datan, MG Pomper, I Minn, P Xu, B Yu
US Patent App. 17/801,509, 2023
2023
Mechanistic Studies of the Transcription Inhibitor Triptolide and its Selective Targeting to Cancer Cells under Hypoxia
E Datan
Johns Hopkins University, 2019
2019
National Asian American and Pacific Islander Heritage Month - Feature Employee
E Datan, JHMOD Inclusion
https://www.linkedin.com/posts/emmanuel-datan-medicine_feature-article-back …, 2018
2018
The NS4A Proteins from 4 Dengue Serotypes, Substantially Different in Sequence, Function Similarly to Induce Autophagy and Protect Mammalian Cells using ATM Pathways
N Zali, SG Roy, E Datan, J McLean, L Alvarez, RA Lockshin, Z Zakeri
2018
Chapter 15: Cell death and virus infection - a short review.
Z Zakeri, S Gosh-Roy, E Datan, J McLean, K Zandi, G Germain
20 Years of Cell Death (LINK is https://www.researchgate.net/publication …, 2015
2015
WJBC
SG Roy, B Sadigh, E Datan, RA Lockshin, Z Zakeri
World 5 (2), 93-105, 2014
2014
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