O27 BMJ Open Gastroenterology best clinical science abstract: endoscopic outcomes from PROFILE: a multi-centre, randomised, open-label, biomarker-stratified clinical trial of … N Noor, J Lee, S Bond, F Dowling, B Brezina, K Patel, T Ahmad, P Banim, ... Gut 73 (Suppl 1), A15-A16, 2024 | | 2024 |
986 ENDOSCOPIC OUTCOMES WITH EARLY TREATMENT IN NEWLYDIAGNOSED CROHN'S DISEASE: EVIDENCE FROM PROFILE, A MULTICENTRE, RANDOMIZED, OPEN-LABEL, BIOMARKER-STRATIFIED CLINICAL TRIAL N Noor, J Lee, S Bond, F Dowling, B Brezina, KV Patel, T Ahmad, ... Gastroenterology 166 (5), S-239-S-240, 2024 | | 2024 |
A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn's disease (PROFILE): a multicentre, open … NM Noor, JC Lee, S Bond, F Dowling, B Brezina, KV Patel, T Ahmad, ... The Lancet Gastroenterology & Hepatology 9 (5), 415-427, 2024 | 38 | 2024 |
OP01 PROFILE: a multi-centre, randomised, open-label, biomarker-stratified clinical trial of treatment strategies for patients with newly-diagnosed Crohn’s disease N Noor, J Lee, S Bond, F Dowling, B Brezina, K Patel, T Ahmad, P Banim, ... Journal of Crohn's and Colitis 18 (Supplement_1), i1-i2, 2024 | 2 | 2024 |
Grp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis CN Spaan, RJ de Boer, WL Smit, JHM van der Meer, M van Roest, ... Life Science Alliance 6 (11), 2023 | 1 | 2023 |
Epithelial argininosuccinate synthetase is dispensable for intestinal regeneration and tumorigenesis JHM van der Meer, RJ de Boer, BJ Meijer, WL Smit, JLM Vermeulen, ... Cell Death & Disease 12 (10), 897, 2021 | 4 | 2021 |
Translation initiation factor eIF2Bε promotes Wnt-mediated clonogenicity and global translation in intestinal epithelial cells WL Smit, RJ de Boer, BJ Meijer, CN Spaan, M van Roest, PJ Koelink, ... Stem Cell Research 55, 102499, 2021 | 4 | 2021 |
Endoplasmic reticulum stress regulates the intestinal stem cell state through CtBP2 BJ Meijer, WL Smit, PJ Koelink, BF Westendorp, RJ de Boer, ... Scientific reports 11 (1), 9892, 2021 | 11 | 2021 |
Epithelium-derived Indian Hedgehog restricts stromal expression of ErbB family members that drive colonic tumor cell proliferation F Westendorp, ON Karpus, PJ Koelink, JLM Vermeulen, S Meisner, ... Oncogene 40 (9), 1628-1643, 2021 | 7 | 2021 |
IL-10 Responsiveness and Anti-TNF Therapy in Inflammatory Bowel Disease FM Bloemendaal, CP Peters, AA te Velde, CY Ponsioen, ... Journal of Cellular Immunology 3 (2), 91-96, 2021 | | 2021 |
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10885 | 2021 |
Sirolimus for the treatment of polyposis of the rectal remnant and ileal pouch in four patients with familial adenomatous polyposis: a pilot study VH Roos, BJ Meijer, FGJ Kallenberg, BAJ Bastiaansen, L Koens, ... BMJ open gastroenterology 7 (1), e000497, 2020 | 15 | 2020 |
Driver mutations of the adenoma-carcinoma sequence govern the intestinal epithelial global translational capacity WL Smit, CN Spaan, R Johannes de Boer, P Ramesh, T Martins Garcia, ... Proceedings of the National Academy of Sciences 117 (41), 25560-25570, 2020 | 66 | 2020 |
Psychological outcomes of a cognitive behavioral therapy for youth with inflammatory bowel disease: results of the HAPPY-IBD randomized controlled trial at 6-and 12-month follow-up L Stapersma, G van den Brink, J van der Ende, EM Szigethy, ... Journal of clinical psychology in medical settings 27, 490-506, 2020 | 25 | 2020 |
Anti-TNF therapy in IBD exerts its therapeutic effect through macrophage IL-10 signalling PJ Koelink, FM Bloemendaal, B Li, L Westera, EWM Vogels, M van Roest, ... Gut 69 (6), 1053-1063, 2020 | 148 | 2020 |
MEX3A regulates Lgr5+ stem cell maintenance in the developing intestinal epithelium B Pereira, AL Amaral, A Dias, N Mendes, V Muncan, AR Silva, C Thibert, ... EMBO reports 21 (4), e48938, 2020 | 28 | 2020 |
Heterocycles capable of modulating t-cell responses, and methods of using same D Hommes, A Verhaar, G Van den Brink, F Viti US Patent 10,562,883, 2020 | 1 | 2020 |
Accelerated intestinal epithelial cell turnover correlates with stimulated bmp signaling cascade following intestinal ischemia–reperfusion in a rat Y Ben-Shahar, Z Abassi, HK Shefer, Y Pollak, U Bhattacharya, I Sukhotnik European Journal of Pediatric Surgery 30 (01), 064-070, 2020 | 3 | 2020 |
A novel organoid model of damage and repair identifies HNF4α as a critical regulator of intestinal epithelial regeneration PS Montenegro-Miranda, JHM van der Meer, C Jones, S Meisner, ... Cellular and Molecular Gastroenterology and Hepatology 10 (2), 209-223, 2020 | 29 | 2020 |
ATF2 and ATF7 are critical mediators of intestinal epithelial repair BJ Meijer, FP Giugliano, B Baan, JHM van der Meer, S Meisner, ... Cellular and molecular gastroenterology and hepatology 10 (1), 23-42, 2020 | 12 | 2020 |