关注
Omid Tavassoly
标题
引用次数
年份
A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease
M Bérard, R Sheta, S Malvaut, R Rodriguez-Aller, M Teixeira, W Idi, ...
Plos Biology 20 (3), e3001578, 2022
132022
Pharmacological functionalization of protein-based nanorobots as a novel tool for drug delivery in cancer
O Tavassoly, I Tavassoly
ACS Pharmacology & Translational Science 4 (4), 1463-1467, 2021
12021
EGFR aggregation in the brain
O Tavassoly, I Tavassoly
ACS Chemical Neuroscience 12 (11), 1833-1834, 2021
42021
Pharmacological inhibition of brain EGFR activation by a BBB-penetrating inhibitor, AZD3759, attenuates α-synuclein pathology in a mouse model of α-synuclein propagation
O Tavassoly, E del Cid Pellitero, F Larroquette, E Cai, RA Thomas, ...
Neurotherapeutics 18, 979-997, 2021
132021
Optogenetic-Mediated Spatiotemporal Control of α-Synuclein Aggregation Mimics Lewy Body Formation and Triggers Neurodegeneration
M Berard, R Sheta, S Malvaut, R Rodriguez-Aller, M Teixeira, W Idi, ...
22021
Pharmacological inhibition and knockdown of OGlcNAcase reduces cellular internalization of αsynuclein preformed fibrils
O Tavassoly, J Yue, DJ Vocadlo
The FEBS journal 288 (2), 452-470, 2021
352021
Seeding brain protein aggregation by SARS-CoV-2 as a possible long-term complication of COVID-19 infection
O Tavassoly, F Safavi, I Tavassoly
ACS Chemical Neuroscience 11 (22), 3704-3706, 2020
642020
Heparin-binding peptides as novel therapies to stop SARS-CoV-2 cellular entry and infection
O Tavassoly, F Safavi, I Tavassoly
Molecular pharmacology 98 (5), 612-619, 2020
412020
Inhibition of brain epidermal growth factor receptor activation: a novel target in neurodegenerative diseases and brain injuries
O Tavassoly, T Sato, I Tavassoly
Molecular pharmacology 98 (1), 13-22, 2020
512020
Optogenetic-Mediated Spatiotemporal Control of α-Synuclein Aggregation Disrupts Nigrostriatal Transmission and Precipitates Neurodegeneration
M Bérard, R Sheta, S Malvaut, R Turmel, MJ Alpaugh, M Dubois, ...
22019
SMPD1 mutations, activity, and αsynuclein accumulation in Parkinson's disease
RN Alcalay, V Mallett, B Vanderperre, O Tavassoly, Y Dauvilliers, RYJ Wu, ...
Movement Disorders 34 (4), 526-535, 2019
1072019
Quinolinic acid amyloid-like fibrillar assemblies seed α-synuclein aggregation
O Tavassoly, D Sade, S Bera, S Shaham-Niv, DJ Vocadlo, E Gazit
Journal of molecular biology 430 (20), 3847-3862, 2018
542018
Seeding of proteins into amyloid structures by metabolite assemblies may clarify certain unexplained epidemiological associations
D Sade, S Shaham-Niv, ZA Arnon, O Tavassoly, E Gazit
Open biology 8 (1), 170229, 2018
332018
SMPD1 mutations, acid-sphingomyelinase activity and alpha-synuclein accumulation in Parkinson's disease
Z Gan-Or, V Mallett, O Tavassoly, Y Dauvilliers, C Leblond, ...
MOVEMENT DISORDERS 31, S220-S220, 2016
2016
Rasagiline, a suicide inhibitor of monoamine oxidases, binds reversibly to α-synuclein
J Kakish, O Tavassoly, JS Lee
ACS chemical neuroscience 6 (2), 347-355, 2015
292015
The use of nanopore analysis for discovering drugs which bind to α-synuclein for treatment of Parkinson's disease
O Tavassoly, J Kakish, S Nokhrin, O Dmitriev, JS Lee
European journal of medicinal chemistry 88, 42-54, 2014
412014
Cu (II) and dopamine bind to αsynuclein and cause large conformational changes
O Tavassoly, S Nokhrin, OY Dmitriev, JS Lee
The FEBS journal 281 (12), 2738-2753, 2014
522014
Single molecule studies of synuclein family of proteins and peptides with nanopores
O Tavassoly
University of Saskatchewan, 2014
2014
Methamphetamine binds to α-synuclein and causes a conformational change which can be detected by nanopore analysis
O Tavassoly, JS Lee
FEBS letters 586 (19), 3222-3228, 2012
542012
Nanopore analysis: An emerging technique for studying the folding and misfolding of proteins
CA Madampage, O Tavassoly, C Christensen, M Kumari, JS Lee
Prion 6 (2), 116-123, 2012
542012
系统目前无法执行此操作,请稍后再试。
文章 1–20