CelltypeR: A flow cytometry pipeline to characterize single cells from brain organoids RA Thomas, J Sirois, S Li, A Gestin, G Deyab, VEC Piscopo, P Lépine, ... iScience, 2024 | | 2024 |
Suggested searches J Howarth, K Vaklinova, M Grzeszczyk, G Baldi, L Hague, M Potemski, ... Perspective, 2024 | | 2024 |
Transcriptomics of Human Brain Tissue in Parkinson’s Disease: a Comparison of Bulk and Single-cell RNA Sequencing MR Fiorini, AA Dilliott, RA Thomas, SMK Farhan Molecular Neurobiology, 1-20, 2024 | 3 | 2024 |
An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders MF Dorion, D Casas, I Shlaifer, M Yaqubi, P Fleming, N Karpilovsky, ... Molecular Neurodegeneration 19 (1), 31, 2024 | | 2024 |
Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress MA Eldeeb, AN Bayne, A Fallahi, T Goiran, EJ MacDougall, A Soumbasis, ... Proceedings of the National Academy of Sciences 121 (10), e2313540121, 2024 | 7 | 2024 |
Machine learning nominates the inositol pathway and novel genes in Parkinson’s disease E Yu, R Larivière, RA Thomas, L Liu, K Senkevich, S Rahayel, JF Trempe, ... Brain 147 (3), 887-899, 2024 | 3 | 2024 |
Ensemblex: an accuracy-weighted ensemble genetic demultiplexing framework for population-scale scRNAseq sample pooling MR Fiorini, S Amiri, AA Dilliott, CM Yde Ohki, L Smigielski, S Walitza, ... bioRxiv, 2024.06. 17.599314, 2024 | | 2024 |
A GENOME-WIDE CRISPR/CAS9 SCREENING IDENTIFIES GENETIC MODIFIERS OF ΑLPHA SYNUCLEIN AGGREGATES UPTAKE B Vanderperre, A Muraleedharan, F Larroquette, R Chidiac, C Tardif, ... IBRO Neuroscience Reports 15, S459, 2023 | | 2023 |
Identification of novel variants, genes and pathways potentially linked to Parkinson’s disease using machine learning E Yu, R Larivière, RA Thomas, L Liu, K Senkevich, S Rahayel, JF Trempe, ... medRxiv, 2023.06. 20.23291658, 2023 | 2 | 2023 |
A deep learning convolutional neural network distinguishes neuronal models of Parkinson's disease from matched controls RA Thomas, E Cai, W Reintsch, C Han, S Shinde, R Lariviere, A Krahn, ... bioRxiv, 2023.11. 23.568499, 2023 | | 2023 |
ScRNAbox: Empowering Single-Cell RNA Sequencing on High Performance Computing Systems RA Thomas, MR Fiorini, S Amiri, EA Fon, SMK Farhan bioRxiv, 2023.11. 13.566851, 2023 | | 2023 |
A genome-wide CRISPR/Cas9 screen identifies genes that regulate the cellular uptake of α-synuclein fibrils by modulating heparan sulfate proteoglycans B Vanderperre, A Muraleedharan, MF Dorion, F Larroquette, ... bioRxiv, 2023.09. 29.560170, 2023 | | 2023 |
CelltypeR: a flow cytometry pipeline to annotate, characterize and isolate single cells from brain organoids RA Thomas, J Sirois, S Li, A Gestin, VE Piscopo, P Lépine, M Mathur, ... bioRxiv, 2022.11. 11.516066, 2022 | 2 | 2022 |
Mitochondrial quality control in health and in Parkinson’s disease MA Eldeeb, RA Thomas, MA Ragheb, A Fallahi, EA Fon Physiological reviews 102 (4), 1721-1755, 2022 | 114 | 2022 |
Auto-qPCR; a python-based web app for automated and reproducible analysis of qPCR data G Maussion, RA Thomas, I Demirova, G Gu, E Cai, CXQ Chen, N Abdian, ... Scientific Reports 11 (1), 21293, 2021 | 13 | 2021 |
Midbrain organoids with an SNCA gene triplication model key features of synucleinopathy NV Mohamed, J Sirois, J Ramamurthy, M Mathur, P Lépine, E Deneault, ... Brain communications 3 (4), fcab223, 2021 | 47 | 2021 |
A multistep workflow to evaluate newly generated iPSCs and their ability to generate different cell types CXQ Chen, N Abdian, G Maussion, RA Thomas, I Demirova, E Cai, ... Methods and protocols 4 (3), 50, 2021 | 45 | 2021 |
Pharmacological inhibition of brain EGFR activation by a BBB-penetrating inhibitor, AZD3759, attenuates α-synuclein pathology in a mouse model of α-synuclein propagation O Tavassoly, E del Cid Pellitero, F Larroquette, E Cai, RA Thomas, ... Neurotherapeutics 18, 979-997, 2021 | 13 | 2021 |
Generation of human midbrain organoids from induced pluripotent stem cells [version 2; peer review: 1 approved, 3 NV Mohamed, M Mathur, RV da Silva, RA Thomas, P Lepine, LK Beitel, ... | | 2021 |
Generation of human midbrain organoids from induced pluripotent stem cells NV Mohamed, M Mathur, RV da Silva, RA Thomas, P Lepine, LK Beitel, ... MNI Open Research 3, 1, 2021 | 19 | 2021 |