SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes P Blache, M Van De Wetering, I Duluc, C Domon, P Berta, JN Freund, ... The Journal of cell biology 166 (1), 37-47, 2004 | 596 | 2004 |
Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium M Jenny, C Uhl, C Roche, I Duluc, V Guillermin, F Guillemot, J Jensen, ... The EMBO journal 21 (23), 6338-6347, 2002 | 574 | 2002 |
Key Role of the Cdx2 Homeobox Gene in Extracellular Matrix–mediated Intestinal Cell Differentiation O Lorentz, I Duluc, AD Arcangelis, P Simon-Assmann, M Kedinger, ... The Journal of cell biology 139 (6), 1553-1565, 1997 | 335 | 1997 |
Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos T Young, JE Rowland, C van de Ven, M Bialecka, A Novoa, M Carapuco, ... Developmental cell 17 (4), 516-526, 2009 | 282 | 2009 |
The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development C Bonhomme, I Duluc, E Martin, K Chawengsaksophak, MP Chenard, ... Gut 52 (10), 1465-1471, 2003 | 276 | 2003 |
Wnt/β-catenin signaling regulates the expression of the homeobox gene Cdx1 in embryonic intestine H Lickert, C Domon, G Huls, C Wehrle, I Duluc, H Clevers, BI Meyer, ... Development 127 (17), 3805-3813, 2000 | 271 | 2000 |
The Cdx-1 and Cdx-2 homeobox genes in the intestine JN Freund, C Domon-Dell, M Kedinger, I Duluc Biochemistry and cell biology 76 (6), 957-969, 1998 | 242 | 1998 |
Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: an active role for the tumor environment in malignant tumor progression T Brabletz, S Spaderna, J Kolb, F Hlubek, G Faller, CJ Bruns, A Jung, ... Cancer research 64 (19), 6973-6977, 2004 | 152 | 2004 |
Intestinal epithelial‐mesenchymal cell interactions M Kedinger, I Duluc, C Fritsch, O Lorentz, M Plateroti, JN Freund Annals of the New York Academy of Sciences 859 (1), 1-17, 1998 | 150 | 1998 |
Fetal endoderm primarily holds the temporal and positional information required for mammalian intestinal development. I Duluc, JN Freund, C Leberquier, M Kedinger The Journal of cell biology 126 (1), 211-221, 1994 | 138 | 1994 |
The intestine-specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancer cells I Gross, I Duluc, T Benameur, A Calon, E Martin, T Brabletz, M Kedinger, ... Oncogene 27 (1), 107-115, 2008 | 137 | 2008 |
Production of low-lactose milk by ectopic expression of intestinal lactase in the mouse mammary gland B Jost, JL Vilotte, I Duluc, JL Rodeau, JN Freund Nature Biotechnology 17 (2), 160-164, 1999 | 114 | 1999 |
Cdx2 determines the fate of postnatal intestinal endoderm EJ Stringer, I Duluc, T Saandi, I Davidson, M Bialecka, T Sato, N Barker, ... Development 139 (3), 465-474, 2012 | 113 | 2012 |
Cellular and molecular partners involved in gut morphogenesis and differentiation M Kedinger, O Lefebvre, I Duluc, JN Freund, P Simon–Assmann Philosophical Transactions of the Royal Society of London. Series B …, 1998 | 108 | 1998 |
Multiple regulatory regions control the complex expression pattern of the mouse Cdx2 homeobox gene F Benahmed, I Gross, SJ Gaunt, F Beck, F Jehan, C Domon–Dell, ... Gastroenterology 135 (4), 1238-1247. e3, 2008 | 102 | 2008 |
Downregulation of the colon tumour-suppressor homeobox gene Cdx-2 by oncogenic ras O Lorentz, A Cadoret, I Duluc, J Capeau, C Gespach, G Cherqui, ... Oncogene 18 (1), 87-92, 1999 | 92 | 1999 |
Primary tumour genetic alterations and intra‐tumoral heterogeneity are maintained in xenografts of human colon cancers showing chromosome instability D Guenot, E Guérin, S Aguillon‐Romain, E Pencreach, A Schneider, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2006 | 91 | 2006 |
Key elements of the BMP/SMAD pathway co‐localize with CDX2 in intestinal metaplasia and regulate CDX2 expression in human gastric cell lines R Barros, B Pereira, I Duluc, M Azevedo, N Mendes, V Camilo, RJ Jacobs, ... The Journal of pathology 215 (4), 411-420, 2008 | 87 | 2008 |
Changing intestinal connective tissue interactions alters homeobox gene expression in epithelial cells IDO Lorentz, C Fritsch, CL Michèle Kedinger, JN Freund Journal of Cell Science 110 (11), 1317-1324, 1997 | 83 | 1997 |
Broader expression of the mouse platelet factor 4‐cre transgene beyond the megakaryocyte lineage F Pertuy, A Aguilar, C Strassel, A Eckly, JN Freund, I Duluc, C Gachet, ... Journal of Thrombosis and Haemostasis 13 (1), 115-125, 2015 | 75 | 2015 |