The contribution of alpha synuclein to neuronal survival and function–Implications for Parkinson's disease MJ Benskey, RG Perez, FP Manfredsson Journal of neurochemistry 137 (3), 331-359, 2016 | 269 | 2016 |
Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology FP Manfredsson, KC Luk, MJ Benskey, A Gezer, J Garcia, NC Kuhn, ... Neurobiology of disease 112, 106-118, 2018 | 170 | 2018 |
Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease Z Zhang, SS Kang, X Liu, EH Ahn, Z Zhang, L He, PM Iuvone, DM Duong, ... Nature structural & molecular biology 24 (8), 632-642, 2017 | 167 | 2017 |
TrkB neurotrophic activities are blocked by α-synuclein, triggering dopaminergic cell death in Parkinson’s disease SS Kang, Z Zhang, X Liu, FP Manfredsson, MJ Benskey, X Cao, J Xu, ... Proceedings of the National Academy of Sciences 114 (40), 10773-10778, 2017 | 110 | 2017 |
Silencing alpha synuclein in mature nigral neurons results in rapid neuroinflammation and subsequent toxicity MJ Benskey, RC Sellnow, IM Sandoval, CE Sortwell, JW Lipton, ... Frontiers in molecular neuroscience 11, 36, 2018 | 98 | 2018 |
Targeted gene delivery to the enteric nervous system using AAV: a comparison across serotypes and capsid mutants MJ Benskey, NC Kuhn, JJ Galligan, J Garcia, SE Boye, WW Hauswirth, ... Molecular Therapy 23 (3), 488-500, 2015 | 72 | 2015 |
Lentivirus production and purification MJ Benskey, FP Manfredsson Gene Therapy for Neurological Disorders: Methods and Protocols, 107-114, 2016 | 61 | 2016 |
Regulation of dopamine neurotransmission from serotonergic neurons by ectopic expression of the dopamine D2 autoreceptor blocks levodopa-induced dyskinesia RC Sellnow, JH Newman, N Chambers, AR West, K Steece-Collier, ... Acta neuropathologica communications 7, 1-17, 2019 | 59 | 2019 |
Continuous collection of adeno-associated virus from producer cell medium significantly increases total viral yield MJ Benskey, IM Sandoval, FP Manfredsson Human gene therapy methods 27 (1), 32-45, 2016 | 45 | 2016 |
Recovery of hypothalamic tuberoinfundibular dopamine neurons from acute toxicant exposure is dependent upon protein synthesis and associated with an increase in parkin and … M Benskey, B Behrouz, J Sunryd, SS Pappas, SH Baek, M Huebner, ... Neurotoxicology 33 (3), 321-331, 2012 | 31 | 2012 |
Sustained resistance to acute MPTP toxicity by hypothalamic dopamine neurons following chronic neurotoxicant exposure is associated with sustained up-regulation of parkin protein M Benskey, KY Lee, K Parikh, KJ Lookingland, JL Goudreau Neurotoxicology 37, 144-153, 2013 | 27 | 2013 |
Intraparenchymal stereotaxic delivery of rAAV and special considerations in vector handling MJ Benskey, FP Manfredsson Gene Therapy for Neurological Disorders: Methods and Protocols, 199-215, 2016 | 26 | 2016 |
Impact of age and vector construct on striatal and nigral transgene expression NK Polinski, FP Manfredsson, MJ Benskey, DL Fischer, CJ Kemp, ... Molecular Therapy Methods & Clinical Development 3, 2016 | 26 | 2016 |
Basic concepts in viral vector-mediated gene therapy MJ Benskey, IM Sandoval, K Miller, RL Sellnow, A Gezer, NC Kuhn, ... Viral Vectors for Gene Therapy: Methods and Protocols, 3-26, 2019 | 13 | 2019 |
The role of parkin in the differential susceptibility of tuberoinfundibular and nigrostriatal dopamine neurons to acute toxicant exposure MJ Benskey, FP Manfredsson, KJ Lookingland, JL Goudreau Neurotoxicology 46, 1-11, 2015 | 11 | 2015 |
Viral Vectors for Gene Therapy FP Manfredsson, MJ Benskey New York, NY: Springer New York, 2019 | 10 | 2019 |
Restoring pars intermedia dopamine concentrations and tyrosine hydroxylase expression levels with pergolide: evidence from horses with pituitary pars intermedia dysfunction JS Fortin, MJ Benskey, KJ Lookingland, JS Patterson, EB Howey, ... BMC veterinary research 16, 1-8, 2020 | 6 | 2020 |
Gene therapy of the peripheral nervous system: the enteric nervous system MJ Benskey, FP Manfredsson Gene Therapy for Neurological Disorders: Methods and Protocols, 263-274, 2016 | 5 | 2016 |
Microglial depletion does not impact alpha-synuclein aggregation or nigrostriatal degeneration in the rat preformed fibril model AC Stoll, CJ Kemp, JR Patterson, M Kubik, N Kuhn, M Benskey, MF Duffy, ... Research Square, 2023 | 2 | 2023 |
Neuroinflammatory gene expression profiles of reactive glia in the substantia nigra suggest a multidimensional immune response to alpha synuclein inclusions AC Stoll, CJ Kemp, JR Patterson, JW Howe, K Steece-Collier, KC Luk, ... Neurobiology of disease 191, 106411, 2024 | 1 | 2024 |