GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists E Eden, R Navon, I Steinfeld, D Lipson, Z Yakhini BMC bioinformatics 10, 1-7, 2009 | 3696 | 2009 |
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing GM Frampton, A Fichtenholtz, GA Otto, K Wang, SR Downing, J He, ... Nature biotechnology 31 (11), 1023-1031, 2013 | 2188 | 2013 |
Blood-based tumor mutational burden as a predictor of clinical benefit in non-small-cell lung cancer patients treated with atezolizumab DR Gandara, SM Paul, M Kowanetz, E Schleifman, W Zou, Y Li, ... Nature medicine 24 (9), 1441-1448, 2018 | 1097 | 2018 |
Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies D Lipson, M Capelletti, R Yelensky, G Otto, A Parker, M Jarosz, JA Curran, ... Nature medicine 18 (3), 382-384, 2012 | 1054 | 2012 |
Discovering motifs in ranked lists of DNA sequences E Eden, D Lipson, S Yogev, Z Yakhini PLoS computational biology 3 (3), e39, 2007 | 843 | 2007 |
Two-state allosteric behavior in a single-domain signaling protein BF Volkman, D Lipson, DE Wemmer, D Kern Science 291 (5512), 2429-2433, 2001 | 768 | 2001 |
Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors GM Frampton, SM Ali, M Rosenzweig, J Chmielecki, X Lu, TM Bauer, ... Cancer discovery 5 (8), 850-859, 2015 | 743 | 2015 |
Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer A Vaishnavi, M Capelletti, AT Le, S Kako, M Butaney, D Ercan, S Mahale, ... Nature medicine 19 (11), 1469-1472, 2013 | 690 | 2013 |
Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor–positive breast cancer R Jeselsohn, R Yelensky, G Buchwalter, G Frampton, F Meric-Bernstam, ... Clinical cancer research 20 (7), 1757-1767, 2014 | 689 | 2014 |
Kinase fusions are frequent in Spitz tumours and spitzoid melanomas T Wiesner, J He, R Yelensky, R Esteve-Puig, T Botton, I Yeh, D Lipson, ... Nature communications 5 (1), 3116, 2014 | 598 | 2014 |
Aberrant overexpression of satellite repeats in pancreatic and other epithelial cancers DT Ting, D Lipson, S Paul, BW Brannigan, S Akhavanfard, EJ Coffman, ... science 331 (6017), 593-596, 2011 | 582 | 2011 |
Response to Cabozantinib in Patients with RET Fusion-Positive Lung Adenocarcinomas A Drilon, L Wang, A Hasanovic, Y Suehara, D Lipson, P Stephens, J Ross, ... Cancer discovery 3 (6), 630-635, 2013 | 552 | 2013 |
Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity H Beltran, R Yelensky, GM Frampton, K Park, SR Downing, ... European urology 63 (5), 920-926, 2013 | 544 | 2013 |
New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing JS Ross, K Wang, L Gay, R Al-Rohil, JV Rand, DM Jones, HJ Lee, ... The oncologist 19 (3), 235-242, 2014 | 499 | 2014 |
Comparative genomic hybridization using oligonucleotide microarrays and total genomic DNA MT Barrett, A Scheffer, A Ben-Dor, N Sampas, D Lipson, R Kincaid, ... Proceedings of the National Academy of Sciences 101 (51), 17765-17770, 2004 | 454 | 2004 |
Inflammatory myofibroblastic tumors harbor multiple potentially actionable kinase fusions CM Lovly, A Gupta, D Lipson, G Otto, T Brennan, CT Chung, ... Cancer discovery 4 (8), 889-895, 2014 | 399 | 2014 |
Methods for detecting fetal nucleic acids and diagnosing fetal abnormalities S Lapidus, JF Thompson, D Lipson, P Milos, JW Efcavitch, S Letovsky US Patent App. 12/727,824, 2010 | 343 | 2010 |
Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms R Rampal, J Ahn, O Abdel-Wahab, M Nahas, K Wang, D Lipson, GA Otto, ... Proceedings of the National Academy of Sciences 111 (50), E5401-E5410, 2014 | 312 | 2014 |
Broad, hybrid capture–based next-generation sequencing identifies actionable genomic alterations in lung adenocarcinomas otherwise negative for such alterations by other … A Drilon, L Wang, ME Arcila, S Balasubramanian, JR Greenbowe, ... Clinical cancer research 21 (16), 3631-3639, 2015 | 301 | 2015 |
Optimization of multigene analysis of tumor samples D Lipson, GA Otto, AN Parker, PJ Stephens, SR Downing, M Jarosz, ... US Patent 9,340,830, 2016 | 291 | 2016 |