| Optimized base editors enable efficient editing in cells, organoids and mice MP Zafra, EM Schatoff, A Katti, M Foronda, M Breinig, AY Schweitzer, ... Nature biotechnology 36 (9), 888-893, 2018 | 327 | 2018 |
| Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer KP O'Rourke, E Loizou, G Livshits, EM Schatoff, T Baslan, E Manchado, ... Nature biotechnology 35 (6), 577-582, 2017 | 231 | 2017 |
| Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis B Palikuqi, DHT Nguyen, G Li, R Schreiner, AF Pellegata, Y Liu, ... Nature 585 (7825), 426-432, 2020 | 191 | 2020 |
| R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine T Han, EM Schatoff, C Murphy, MP Zafra, JE Wilkinson, O Elemento, ... Nature communications 8 (1), 15945, 2017 | 113 | 2017 |
| Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets F Tang, D Xu, S Wang, CK Wong, A Martinez-Fundichely, CJ Lee, ... Science 376 (6596), eabe1505, 2022 | 110 | 2022 |
| An In Vivo Kras Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants MP Zafra, MJ Parsons, J Kim, D Alonso-Curbelo, S Goswami, EM Schatoff, ... Cancer discovery 10 (11), 1654-1671, 2020 | 96 | 2020 |
| Lineage reversion drives WNT independence in intestinal cancer T Han, S Goswami, Y Hu, F Tang, MP Zafra, C Murphy, Z Cao, JT Poirier, ... Cancer discovery 10 (10), 1590-1609, 2020 | 61 | 2020 |
| Differential effects of macrophage subtypes on SARS-CoV-2 infection in a human pluripotent stem cell-derived model Q Lian, K Zhang, Z Zhang, F Duan, L Guo, W Luo, BWY Mok, A Thakur, ... Nature communications 13 (1), 2028, 2022 | 54 | 2022 |
| Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression S Choi, D Wang, X Chen, LH Tang, A Verma, Z Chen, BJ Kim, L Selesner, ... Molecular cancer 18, 1-7, 2019 | 47 | 2019 |
| Modeling COVID-19 with human pluripotent stem cell-derived cells reveals synergistic effects of anti-inflammatory macrophages with ACE2 inhibition against SARS-CoV-2 F Duan, L Guo, L Yang, Y Han, A Thakur, BE Nilsson-Payant, P Wang, ... Research square, 2020 | 46 | 2020 |
| Somatic tissue engineering in mouse models reveals an actionable role for WNT pathway alterations in prostate cancer metastasis J Leibold, M Ruscetti, Z Cao, YJ Ho, T Baslan, M Zou, W Abida, J Feucht, ... Cancer discovery 10 (7), 1038-1057, 2020 | 46 | 2020 |
| Exploiting the therapeutic interaction of WNT pathway activation and asparaginase for colorectal cancer therapy L Hinze, R Labrosse, J Degar, T Han, EM Schatoff, S Schreek, S Karim, ... Cancer discovery 10 (11), 1690-1705, 2020 | 43 | 2020 |
| The E3/E4 ubiquitin conjugation factor UBE4B interacts with and ubiquitinates the HTLV-1 Tax oncoprotein to promote NF-κB activation S Mohanty, T Han, YB Choi, A Lavorgna, J Zhang, EW Harhaj PLoS pathogens 16 (12), e1008504, 2020 | 19 | 2020 |
| Rapid interrogation of cancer cell of origin through CRISPR editing W Feng, Z Cao, PX Lim, H Zhao, H Luo, N Mao, YS Lee, AA Rivera, ... Proceedings of the National Academy of Sciences 118 (32), e2110344118, 2021 | 17 | 2021 |
| Somatic Tissue Engineering in Mouse Models Reveals an Actionable Role for WNT Pathway Alterations in Prostate Cancer Metastasis. Cancer Discov. 2020; 10: 1038–1057. doi: 10 … J Leibold, M Ruscetti, Z Cao, YJ Ho, T Baslan, M Zou, W Abida, J Feucht, ... CD-19-1242.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 6 | |
| Comprehensive microRNA analysis across genome-edited colorectal cancer organoid models reveals miR-24 as a candidate regulator of cell survival JW Villanueva, L Kwong, T Han, SA Martinez, MT Shanahan, M Kanke, ... Bmc Genomics 23 (1), 792, 2022 | 5 | 2022 |
| Chromatin accessibility profiles of castration-resistant prostate cancers reveal novel subtypes and therapeutic vulnerabilities F Tang, S Wang, CK Wong, CJ Lee, S Cohen, J Park, CE Hill, K Eng, ... bioRxiv, 2020.10. 26.355925, 2020 | 5 | 2020 |
| An optimized toolkit for precision base editing MP Zafra, EM Schatoff, A Katti, M Foronda, M Breinig, AY Schweitzer, ... bioRxiv, 303131, 2018 | 1 | 2018 |
| Abstract NG10: Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets F Tang, D Xu, S Wang, CK Wong, A Martinez-Fundichely, CJ Lee, ... Cancer Research 83 (7_Supplement), NG10-NG10, 2023 | | 2023 |
| Abstract B026: Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets F Tang, D Xu, S Wang, CK Wong, A Martinez-Fundichely, C Lee, S Cohen, ... Cancer Research 82 (23_Supplement_2), B026-B026, 2022 | | 2022 |
