Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease Z Zhang, SS Kang, X Liu, EH Ahn, Z Zhang, L He, PM Iuvone, DM Duong, ... Nature structural & molecular biology 24 (8), 632-642, 2017 | 169 | 2017 |
Gut dysbiosis contributes to amyloid pathology, associated with C/EBPβ/AEP signaling activation in Alzheimer’s disease mouse model C Chen, EH Ahn, SS Kang, X Liu, A Alam, K Ye Science advances 6 (31), eaba0466, 2020 | 134 | 2020 |
α‐Synuclein stimulation of monoamine oxidase‐B and legumain protease mediates the pathology of Parkinson's disease SS Kang, EH Ahn, Z Zhang, X Liu, FP Manfredsson, IM Sandoval, ... The EMBO journal 37 (12), e98878, 2018 | 89 | 2018 |
Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus SS Kang, X Liu, EH Ahn, J Xiang, FP Manfredsson, X Yang, HR Luo, ... The Journal of clinical investigation 130 (1), 422-437, 2020 | 83 | 2020 |
Initiation of Parkinson’s disease from gut to brain by δ-secretase EH Ahn, SS Kang, X Liu, G Chen, Z Zhang, B Chandrasekharan, AM Alam, ... Cell research 30 (1), 70-87, 2020 | 81 | 2020 |
Gut inflammation triggers C/EBPβ/δ‐secretase‐dependent gut‐to‐brain propagation of Aβ and Tau fibrils in Alzheimer’s disease C Chen, Y Zhou, H Wang, A Alam, SS Kang, EH Ahn, X Liu, J Jia, K Ye The EMBO Journal 40 (17), e106320, 2021 | 80 | 2021 |
Transduced PEP-1-FK506BP ameliorates atopic dermatitis in NC/Nga mice SY Kim, EJ Sohn, DW Kim, HJ Jeong, MJ Kim, HW Kang, MJ Shin, ... Journal of investigative dermatology 131 (7), 1477-1485, 2011 | 62 | 2011 |
Delta-secretase-cleaved Tau antagonizes TrkB neurotrophic signalings, mediating Alzheimer’s disease pathologies J Xiang, ZH Wang, EH Ahn, X Liu, SP Yu, FP Manfredsson, IM Sandoval, ... Proceedings of the National Academy of Sciences 116 (18), 9094-9102, 2019 | 61 | 2019 |
Tat-glyoxalase protein inhibits against ischemic neuronal cell damage and ameliorates ischemic injury MJ Shin, DW Kim, YP Lee, EH Ahn, HS Jo, DS Kim, OS Kwon, TC Kang, ... Free Radical Biology and Medicine 67, 195-210, 2014 | 61 | 2014 |
Transduced PEP-1-ribosomal protein S3 (rpS3) ameliorates 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice EH Ahn, DW Kim, HW Kang, MJ Shin, MH Won, J Kim, DJ Kim, OS Kwon, ... Toxicology 276 (3), 192-197, 2010 | 49 | 2010 |
Netrin‐1 and its receptor DCC modulate survival and death of dopamine neurons and Parkinson’s disease features M Jasmin, EH Ahn, MH Voutilainen, J Fombonne, C Guix, T Viljakainen, ... The EMBO journal 40 (3), e105537, 2021 | 46 | 2021 |
Transduced human PEP-1–catalase fusion protein attenuates ischemic neuronal damage DW Kim, HJ Jeong, HW Kang, MJ Shin, EJ Sohn, MJ Kim, EH Ahn, JJ An, ... Free Radical Biology and Medicine 47 (7), 941-952, 2009 | 45 | 2009 |
PEP-1–ribosomal protein S3 protects dopaminergic neurons in an MPTP-induced Parkinson's disease mouse model EH Ahn, DW Kim, MJ Shin, YN Kim, HR Kim, SJ Woo, SM Kim, DS Kim, ... Free Radical Biology and Medicine 55, 36-45, 2013 | 43 | 2013 |
Development of an α-synuclein positron emission tomography tracer for imaging synucleinopathies J Xiang, Y Tao, Y Xia, S Luo, Q Zhao, B Li, X Zhang, Y Sun, W Xia, ... Cell 186 (16), 3350-3367. e19, 2023 | 41 | 2023 |
Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma K Lei, X Gu, AG Alvarado, Y Du, S Luo, EH Ahn, SS Kang, B Ji, X Liu, ... Journal of hematology & oncology 13, 1-21, 2020 | 41 | 2020 |
Netrin1 deficiency activates MST1 via UNC5B receptor, promoting dopaminergic apoptosis in Parkinson’s disease EH Ahn, SS Kang, Q Qi, X Liu, K Ye Proceedings of the National Academy of Sciences 117 (39), 24503-24513, 2020 | 41 | 2020 |
Chlorogenic acid improves neuroprotective effect of PEP-1-ribosomal protein S3 against ischemic insult EH Ahn, DW Kim, MJ Shin, SW Kwon, YN Kim, DS Kim, SS Lim, J Kim, ... Experimental Neurobiology 20 (4), 169, 2011 | 38 | 2011 |
Neuroprotective effects of PEP-1-carbonyl reductase 1 against oxidative-stress-induced ischemic neuronal cell damage YN Kim, HY Jung, WS Eum, DW Kim, MJ Shin, EH Ahn, SJ Kim, CH Lee, ... Free Radical Biology and Medicine 69, 181-196, 2014 | 37 | 2014 |
C/EBPβ mediates NQO1 and GSTP1 anti-oxidative reductases expression in glioblastoma, promoting brain tumor proliferation K Lei, Y Xia, XC Wang, EH Ahn, L Jin, K Ye Redox biology 34, 101578, 2020 | 34 | 2020 |
ApoE4 inhibition of VMAT2 in the locus coeruleus exacerbates Tau pathology in Alzheimer’s disease SS Kang, EH Ahn, X Liu, M Bryson, GW Miller, D Weinshenker, K Ye Acta neuropathologica 142, 139-158, 2021 | 33 | 2021 |