The polygenic and monogenic basis of blood traits and diseases D Vuckovic, EL Bao, P Akbari, CA Lareau, A Mousas, T Jiang, MH Chen, ... Cell 182 (5), 1214-1231. e11, 2020 | 448 | 2020 |
The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation SA Lambert, L Gil, S Jupp, SC Ritchie, Y Xu, A Buniello, A McMahon, ... Nature Genetics 53 (4), 420-425, 2021 | 386 | 2021 |
Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort Y Qin, AS Havulinna, Y Liu, P Jousilahti, SC Ritchie, A Tokolyi, ... Nature Genetics 54 (2), 134-142, 2022 | 215 | 2022 |
The biomarker GlycA is associated with chronic inflammation and predicts long-term risk of severe infection SC Ritchie, P Würtz, AP Nath, G Abraham, AS Havulinna, LG Fearnley, ... Cell systems 1 (4), 293-301, 2015 | 213 | 2015 |
FastSpar: rapid and scalable correlation estimation for compositional data SC Watts, SC Ritchie, M Inouye, KE Holt Bioinformatics 35 (6), 1064-1066, 2019 | 211 | 2019 |
Polygenic risk scores in cardiovascular risk prediction: A cohort study and modelling analyses L Sun, L Pennells, S Kaptoge, CP Nelson, SC Ritchie, G Abraham, ... PLoS medicine 18 (1), e1003498, 2021 | 120 | 2021 |
Power, false discovery rate and Winner’s Curse in eQTL studies QQ Huang, SC Ritchie, M Brozynska, M Inouye Nucleic acids research 46 (22), e133-e133, 2018 | 113 | 2018 |
Experimental and Human Evidence for Lipocalin‐2 (Neutrophil Gelatinase‐Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure FZ Marques, PR Prestes, SG Byars, SC Ritchie, P Würtz, SK Patel, ... Journal of the American Heart Association 6 (6), e005971, 2017 | 75 | 2017 |
A Scalable Permutation Approach Reveals Replication and Preservation Patterns of Network Modules in Large Datasets SC Ritchie, S Watts, LG Fearnley, KE Holt, G Abraham, M Inouye Cell Systems 3 (1), 71-82, 2016 | 61 | 2016 |
Comparative analysis reveals a role for TGF-β in shaping the residency-related transcriptional signature in tissue-resident memory CD8+ T cells AP Nath, A Braun, SC Ritchie, FR Carbone, LK Mackay, T Gebhardt, ... PLOS One 14 (2), e0210495, 2019 | 55 | 2019 |
Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases SC Ritchie, SA Lambert, M Arnold, SM Teo, S Lim, P Scepanovic, ... Nature metabolism 3 (11), 1476-1483, 2021 | 51 | 2021 |
Quality control and removal of technical variation of NMR metabolic biomarker data in~ 120,000 UK Biobank participants SC Ritchie, P Surendran, S Karthikeyan, SA Lambert, T Bolton, L Pennells, ... Scientific Data 10 (1), 64, 2023 | 49 | 2023 |
Biomarker Glycoprotein Acetyls Is Associated With the Risk of a Wide Spectrum of Incident Diseases and Stratifies Mortality Risk in Angiography Patients J Kettunen, SC Ritchie, O Anufrieva, LP Lyytikäinen, J Hernesniemi, ... Circulation: Genomic and Precision Medicine 11 (11), e002234, 2018 | 49 | 2018 |
An interaction map of circulating metabolites, immune gene networks, and their genetic regulation AP Nath, SC Ritchie, SG Byars, LG Fearnley, AS Havulinna, A Joensuu, ... Genome Biology 18 (1), 146, 2017 | 46 | 2017 |
An atlas of genetic scores to predict multi-omic traits Y Xu, SC Ritchie, Y Liang, PRHJ Timmers, M Pietzner, L Lannelongue, ... Nature 616 (7955), 123-131, 2023 | 41 | 2023 |
Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy AP Nath, SC Ritchie, NF Grinberg, HHF Tang, QQ Huang, SM Teo, ... The American Journal of Human Genetics 105 (6), 1076-1090, 2019 | 31 | 2019 |
Neonatal genetics of gene expression reveal potential origins of autoimmune and allergic disease risk QQ Huang, HHF Tang, SM Teo, D Mok, SC Ritchie, AP Nath, M Brozynska, ... Nature communications 11 (1), 3761, 2020 | 30 | 2020 |
Machine learning optimized polygenic scores for blood cell traits identify sex-specific trajectories and genetic correlations with disease Y Xu, D Vuckovic, SC Ritchie, P Akbari, T Jiang, J Grealey, AS Butterworth, ... Cell Genomics 2 (1), 100086, 2022 | 19* | 2022 |
Elevated serum alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality SC Ritchie, J Kettunen, M Brozynska, AP Nath, AS Havulinna, S Männistö, ... PLOS One 14 (10), e0223692, 2019 | 18 | 2019 |
Genetically personalised organ-specific metabolic models in health and disease C Foguet, Y Xu, SC Ritchie, SA Lambert, E Persyn, AP Nath, ... Nature Communications 13 (1), 7356, 2022 | 11 | 2022 |