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Carrie L Shaffer, PhD
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引用次数
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Human and Helicobacter pylori coevolution shapes the risk of gastric disease
N Kodaman, A Pazos, BG Schneider, MB Piazuelo, R Mera, RS Sobota, ...
Proceedings of the National Academy of Sciences 111 (4), 1455-1460, 2014
3012014
Phylogeographic origin of Helicobacter pylori is a determinant of gastric cancer risk
T de Sablet, MB Piazuelo, CL Shaffer, BG Schneider, M Asim, ...
Gut 60 (9), 1189-1195, 2011
1892011
Helicobacter pylori exploits a unique repertoire of type IV secretion system components for pilus assembly at the bacteria-host cell interface
CL Shaffer, JA Gaddy, JT Loh, EM Johnson, S Hill, EE Hennig, ...
PLoS Pathogens 7 (9), e1002237, 2011
1702011
Genome sequence analysis of Helicobacter pylori strains associated with gastric ulceration and gastric cancer
MS McClain, CL Shaffer, DA Israel, RM Peek, TL Cover
BMC Genomics 10 (1), 3, 2009
1342009
Downregulated Th17 responses are associated with reduced gastritis in Helicobacter pylori–infected children
C Serrano, SW Wright, D Bimczok, CL Shaffer, TL Cover, A Venegas, ...
Mucosal Immunology 6 (5), 950, 2013
117*2013
Pathogenic H elicobacter pylori strains translocate DNA and activate TLR9 via the cancer-associated cag type IV secretion system
MG Varga, CL Shaffer, JC Sierra, G Suarez, MB Piazuelo, ME Whitaker, ...
Oncogene 35 (48), 6262-6269, 2016
1072016
Strong cross-system interactions drive the activation of the QseB response regulator in the absence of its cognate sensor
KR Guckes, M Kostakioti, EJ Breland, AP Gu, CL Shaffer, CR Martinez III, ...
Proceedings of the National Academy of Sciences 110 (41), 16592-16597, 2013
942013
Adhesive fiber stratification in uropathogenic Escherichia coli biofilms unveils oxygen-mediated control of type 1 pili
KA Floyd, JL Moore, AR Eberly, JAD Good, CL Shaffer, H Zaver, ...
PLoS Pathogens 11 (3), e1004697, 2015
922015
Analysis of cagA in Helicobacter pylori Strains from Colombian Populations with Contrasting Gastric Cancer Risk Reveals a Biomarker for Disease Severity
JT Loh, CL Shaffer, MB Piazuelo, LE Bravo, MS McClain, P Correa, ...
Cancer epidemiology, biomarkers & prevention 20 (10), 2237-2249, 2011
822011
Molecular evolution of the Helicobacter pylori vacuolating toxin gene vacA
KA Gangwer, CL Shaffer, S Suerbaum, DB Lacy, TL Cover, ...
Journal of Bacteriology 192 (23), 6126-6135, 2010
792010
In vivo structures of the Helicobacter pylori cag type IV secretion system
YW Chang, CL Shaffer, LA Rettberg, D Ghosal, GJ Jensen
Cell Reports 23 (3), 673-681, 2018
772018
Pilicide ec240 disrupts virulence circuits in uropathogenic Escherichia coli
SE Greene, JS Pinkner, E Chorell, KW Dodson, CL Shaffer, MS Conover, ...
MBio 5 (6), 10.1128/mbio. 02038-14, 2014
752014
Purine biosynthesis metabolically constrains intracellular survival of uropathogenic Escherichia coli
CL Shaffer, EW Zhang, AG Dudley, BREA Dixon, KR Guckes, EJ Breland, ...
Infection and Immunity 85 (1), e00471-16, 2017
472017
Peptidomimetic small molecules disrupt type IV secretion system activity in diverse bacterial pathogens
CL Shaffer, JAD Good, S Kumar, KS Krishnan, JA Gaddy, JT Loh, ...
MBio 7 (2), e00221-16, 2016
462016
Comparative genomic analysis of East Asian and non-Asian Helicobacter pylori strains identifies rapidly evolving genes
SS Duncan, PL Valk, MS McClain, CL Shaffer, JA Metcalf, SR Bordenstein, ...
PloS One 8 (1), e55120, 2013
382013
Inhibiting bacterial secretion systems in the fight against antibiotic resistance
E Boudaher, CL Shaffer
Medchemcomm 10 (5), 682-692, 2019
292019
J-Western forms of Helicobacter pylori cagA constitute a distinct phylogenetic group with a widespread geographic distribution
SS Duncan, PL Valk, CL Shaffer, SR Bordenstein, TL Cover
Journal of Bacteriology, JB. 06340-11, 2012
272012
In situ imaging of bacterial outer membrane projections and associated protein complexes using electron cryo-tomography
M Kaplan, G Chreifi, LA Metskas, J Liedtke, CR Wood, CM Oikonomou, ...
Elife 10, e73099, 2021
152021
Immunostimulatory membrane proteins potentiate H. pylori-induced carcinogenesis by enabling CagA translocation
MG Varga, CR Wood, J Butt, ME Ryan, WC You, K Pan, T Waterboer, ...
Gut microbes 13 (1), 1862613, 2021
132021
Novel transient cytoplasmic rings stabilize assembling bacterial flagellar motors
M Kaplan, CM Oikonomou, CR Wood, G Chreifi, P Subramanian, ...
The EMBO Journal 41 (10), e109523, 2022
112022
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