The re-emergence of natural products for drug discovery in the genomics era AL Harvey, RA Edrada-Ebel, RJ Quinn Nature reviews drug discovery 14 (2), 111-129, 2015 | 2692 | 2015 |
Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors A Maresca, C Temperini, H Vu, NB Pham, SA Poulsen, A Scozzafava, ... Journal of the American Chemical Society 131 (8), 3057-3062, 2009 | 550 | 2009 |
Adenosine receptors: new opportunities for future drugs SA Poulsen, RJ Quinn Bioorganic & medicinal chemistry 6 (6), 619-641, 1998 | 426 | 1998 |
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ... PLoS pathogens 12 (7), e1005763, 2016 | 298 | 2016 |
Elicitation of secondary metabolism in actinomycetes UR Abdelmohsen, T Grkovic, S Balasubramanian, MS Kamel, RJ Quinn, ... Biotechnology advances 33 (6), 798-811, 2015 | 281 | 2015 |
Maculotoxin: a neurotoxin from the venom glands of the octopus Hapalochlaena maculosa identified as tetrodotoxin DD Sheumack, MEH Howden, I Spence, RJ Quinn Science 199, 188-189, 1978 | 278 | 1978 |
Flinderoles A−C: Antimalarial Bis-indole Alkaloids from Flindersia Species LS Fernandez, MS Buchanan, AR Carroll, YJ Feng, RJ Quinn, VM Avery Organic Letters 11 (2), 329-332, 2009 | 238 | 2009 |
Developing a drug-like natural product library RJ Quinn, AR Carroll, NB Pham, P Baron, ME Palframan, L Suraweera, ... Journal of natural products 71 (3), 464-468, 2008 | 222 | 2008 |
Drug-like properties: guiding principles for the design of natural product libraries D Camp, RA Davis, M Campitelli, J Ebdon, RJ Quinn Journal of natural products 75 (1), 72-81, 2012 | 205 | 2012 |
Dereplication strategies for targeted isolation of new antitrypanosomal actinosporins A and B from a marine sponge associated-Actinokineospora sp. EG49 UR Abdelmohsen, C Cheng, C Viegelmann, T Zhang, T Grkovic, S Ahmed, ... Marine drugs 12 (3), 1220-1244, 2014 | 186 | 2014 |
Phospholipase A2 in cnidaria TJ Nevalainen, HJ Peuravuori, RJ Quinn, LE Llewellyn, JAH Benzie, ... Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular …, 2004 | 186 | 2004 |
Axinellamines A−D, Novel Imidazo−Azolo−Imidazole Alkaloids from the Australian Marine Sponge Axinella sp. S Urban, P de Almeida Leone, AR Carroll, GA Fechner, J Smith, ... The Journal of organic chemistry 64 (3), 731-735, 1999 | 169 | 1999 |
New Lamellarin Alkaloids from the Australian Ascidian, Didemnum chartaceum RA Davis, AR Carroll, GK Pierens, RJ Quinn Journal of natural products 62 (3), 419-424, 1999 | 158 | 1999 |
Potential of marine natural products against drug-resistant fungal, viral, and parasitic infections UR Abdelmohsen, S Balasubramanian, TA Oelschlaeger, T Grkovic, ... The Lancet Infectious Diseases 17 (2), e30-e41, 2017 | 155 | 2017 |
Production of Induced Secondary Metabolites by a Co-Culture of Sponge-Associated Actinomycetes, Actinokineospora sp. EG49 and Nocardiopsis sp. RV163 Y Dashti, T Grkovic, UR Abdelmohsen, U Hentschel, RJ Quinn Marine drugs 12 (5), 3046-3059, 2014 | 152 | 2014 |
The fatty acid synthase inhibitor triclosan: repurposing an anti-microbial agent for targeting prostate cancer MC Sadowski, RH Pouwer, JH Gunter, AA Lubik, RJ Quinn, CC Nelson Oncotarget 5 (19), 9362, 2014 | 147 | 2014 |
Biodiversity ‘hotspots’, patterns of richness and endemism, and taxonomic affinities of tropical Australian sponges (Porifera) JNA Hooper, JA Kennedy, RJ Quinn Biodiversity & Conservation 11, 851-885, 2002 | 144 | 2002 |
Direct screening of natural product extracts using mass spectrometry H Vu, NB Pham, RJ Quinn SLAS Discovery 13 (4), 265-275, 2008 | 143 | 2008 |
Natural Products, Stylissadines A and B, Specific Antagonists of the P2X7 Receptor, an Important Inflammatory Target1 MS Buchanan, AR Carroll, R Addepalli, VM Avery, JNA Hooper, RJ Quinn The Journal of organic chemistry 72 (7), 2309-2317, 2007 | 136 | 2007 |
A new class of halogenated lactones from the red alga Delisea fimbriata (Bonnemaisoniaceae) R Kazlauskas, PT Murphy, RJ Quinn, RJ Wells Tetrahedron Letters 18 (1), 37-40, 1977 | 133 | 1977 |