| The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease YH Youm, KY Nguyen, RW Grant, EL Goldberg, M Bodogai, D Kim, ... Nature medicine 21 (3), 263-269, 2015 | 1811 | 2015 |
| Multi-dimensional roles of ketone bodies in fuel metabolism, signaling, and therapeutics P Puchalska, PA Crawford Cell metabolism 25 (2), 262-284, 2017 | 1313 | 2017 |
| Nonalcoholic steatohepatitis: a review AC Sheka, O Adeyi, J Thompson, B Hameed, PA Crawford, S Ikramuddin Jama 323 (12), 1175-1183, 2020 | 1084 | 2020 |
| The failing heart relies on ketone bodies as a fuel G Aubert, OJ Martin, JL Horton, L Lai, RB Vega, TC Leone, T Koves, ... Circulation 133 (8), 698-705, 2016 | 642 | 2016 |
| Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal … Y Sadovsky, PA Crawford, KG Woodson, JA Polish, MA Clements, ... Proceedings of the national academy of sciences 92 (24), 10939-10943, 1995 | 525 | 1995 |
| Ketone body metabolism and cardiovascular disease DG Cotter, RC Schugar, PA Crawford American Journal of Physiology-Heart and Circulatory Physiology, 2013 | 479 | 2013 |
| Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1 PA Crawford, C Dorn, Y Sadovsky, J Milbrandt Molecular and Cellular Biology, 1998 | 389 | 1998 |
| RET signaling is essential for migration, axonal growth and axon guidance of developing sympathetic neurons H Enomoto, PA Crawford, A Gorodinsky, RO Heuckeroth, EM Johnson Jr, ... Oxford University Press for The Company of Biologists Limited 128 (20), 3963 …, 2001 | 324 | 2001 |
| The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense JL Horton, MT Davidson, C Kurishima, RB Vega, JC Powers, TR Matsuura, ... JCI insight 4 (4), 2019 | 274 | 2019 |
| Regulation of myocardial ketone body metabolism by the gut microbiota during nutrient deprivation PA Crawford, JR Crowley, N Sambandam, BD Muegge, EK Costello, ... Proceedings of the National Academy of Sciences 106 (27), 11276-11281, 2009 | 274 | 2009 |
| Lactate metabolism is associated with mammalian mitochondria YJ Chen, NG Mahieu, X Huang, M Singh, PA Crawford, SL Johnson, ... Nature chemical biology 12 (11), 937-943, 2016 | 269 | 2016 |
| Microbial regulation of intestinal radiosensitivity PA Crawford, JI Gordon Proceedings of the National Academy of Sciences 102 (37), 13254-13259, 2005 | 266 | 2005 |
| Activation of luteinizing hormone β gene by gonadotropin-releasing hormone requires the synergy of early growth response-1 and steroidogenic factor-1 C Dorn, Q Ou, J Svaren, PA Crawford, Y Sadovsky Journal of Biological Chemistry 274 (20), 13870-13876, 1999 | 204 | 1999 |
| Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia DG Cotter, B Ercal, X Huang, JM Leid, DA d’Avignon, MJ Graham, ... The Journal of clinical investigation 124 (12), 5175-5190, 2014 | 200 | 2014 |
| Adrenocortical function and regulation of the steroid 21-hydroxylase gene in NGFI-B-deficient mice PA Crawford, Y Sadovsky, K Woodson, SL Lee, J Milbrandt Molecular and cellular biology, 1995 | 195 | 1995 |
| Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet JR Garbow, JM Doherty, RC Schugar, S Travers, ML Weber, AE Wentz, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 300 (6 …, 2011 | 186 | 2011 |
| X13CMS: Global Tracking of Isotopic Labels in Untargeted Metabolomics X Huang, YJ Chen, K Cho, I Nikolskiy, PA Crawford, GJ Patti Analytical chemistry 86 (3), 1632-1639, 2014 | 178 | 2014 |
| Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling RC Schugar, AR Moll, DA d’Avignon, CJ Weinheimer, A Kovacs, ... Molecular metabolism 3 (7), 754-769, 2014 | 174 | 2014 |
| Nuclear receptor steroidogenic factor 1 directs embryonic stem cells toward the steroidogenic lineage PA Crawford, Y Sadovsky, J Milbrandt Molecular and cellular biology, 1997 | 163 | 1997 |
| Low-carbohydrate ketogenic diets, glucose homeostasis, and nonalcoholic fatty liver disease RC Schugar, PA Crawford Current Opinion in Clinical Nutrition & Metabolic Care 15 (4), 374-380, 2012 | 143 | 2012 |
