Omega-3 versus Omega-6 fatty acid availability is controlled by hydrophobic site geometries of phospholipase A2s D Hayashi, VD Mouchlis, EA Dennis Journal of Lipid Research 62, 2021 | 37 | 2021 |
Depression of type I diacylglycerol kinases in pancreatic β-cells from male mice results in impaired insulin secretion Y Kurohane Kaneko, Y Kobayashi, K Motoki, K Nakata, S Miyagawa, ... Endocrinology 154 (11), 4089-4098, 2013 | 34 | 2013 |
Diacylglycerol kinase alpha is involved in the vitamin E-induced amelioration of diabetic nephropathy in mice D Hayashi, K Yagi, C Song, S Ueda, M Yamanoue, M Topham, T Suzaki, ... Scientific reports 7 (1), 2597, 2017 | 33 | 2017 |
Each phospholipase A2 type exhibits distinct selectivity toward sn-1 ester, alkyl ether, and vinyl ether phospholipids D Hayashi, VD Mouchlis, EA Dennis Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2022 | 21 | 2022 |
The mechanisms of ameliorating effect of a green tea polyphenol on diabetic nephropathy based on diacylglycerol kinase α D Hayashi, L Wang, S Ueda, M Yamanoue, H Ashida, Y Shirai Scientific Reports 10 (1), 11790, 2020 | 21 | 2020 |
Lipoprotein-associated phospholipase A2: A paradigm for allosteric regulation by membranes VD Mouchlis, D Hayashi, AM Vasquez, J Cao, JA McCammon, EA Dennis Proceedings of the National Academy of Sciences 119 (2), e2102953118, 2022 | 18 | 2022 |
Epigallocatechin-3-gallate activates diacylglycerol kinase alpha via a 67 kDa laminin receptor: A possibility of galloylated catechins as functional food to prevent and/or … D Hayashi, S Ueda, M Yamanoue, N Saito, H Ashida, Y Shirai Journal of functional foods 15, 561-569, 2015 | 13 | 2015 |
Amelioration of diabetic nephropathy by oral administration of d-α-tocopherol and its mechanisms D Hayashi, S Ueda, M Yamanoue, H Ashida, Y Shirai Bioscience, Biotechnology, and Biochemistry 82 (1), 65-73, 2018 | 11 | 2018 |
Vitamin E functions by association with a novel binding site on the 67 kDa laminin receptor activating diacylglycerol kinase D Hayashi, VD Mouchlis, S Okamoto, T Namba, L Wang, S Li, S Ueda, ... The Journal of nutritional biochemistry 110, 109129, 2022 | 6 | 2022 |
The role of diacylglycerol kinase in the amelioration of diabetic nephropathy D Hayashi, Y Shirai Molecules 27 (20), 6784, 2022 | 5 | 2022 |
2-Oxoester Phospholipase A2 Inhibitors with Enhanced Metabolic Stability GS Koutoulogenis, MG Kokotou, D Hayashi, VD Mouchlis, EA Dennis, ... Biomolecules 10 (3), 491, 2020 | 5 | 2020 |
Molecular basis of unique specificity and regulation of group VIA calcium-independent phospholipase A2 (PNPLA9) and its role in neurodegenerative diseases D Hayashi, EA Dennis Pharmacology & Therapeutics, 108395, 2023 | 4 | 2023 |
Screening of subtype-specific activators and inhibitors for diacylglycerol kinase D Hayashi, R Tsumagari, K Liu, S Ueda, M Yamanoue, F Sakane, Y Shirai The journal of biochemistry 165 (6), 517-522, 2019 | 3 | 2019 |
N-Acylated and N-Alkylated 2-Aminobenzothiazoles Are Novel Agents That Suppress the Generation of Prostaglandin E2 MA Theodoropoulou, A Psarra, M Erhardt, A Nikolaou, ... Biomolecules 12 (2), 267, 2022 | 1 | 2022 |
Unique enzyme specificity of three human phospholipases A2 toward phospholipids containing sn‐2 omega‐3 and omega‐6 fatty acids D Hayashi, VD Mouchlis, EA Dennis The FASEB Journal 33 (S1), 489.4-489.4, 2019 | 1 | 2019 |
Unique Substrate Specificity of Human Phospholipase A2s D Hayashi, VD Mouchlis, EA Dennis The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |
Interfacial activation of lipolytic enzymes by cellular membranes V Mouchlis, D Hayashi, J McCammon, E Dennis ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
Protective Role of Alpha-Tocopherol in Diabetic Nephropathy D Hayashi, Y Shirai Nutritional and Therapeutic Interventions for Diabetes and Metabolic …, 2018 | | 2018 |
Vitamin E activates diacylglycerol kinase alpha (DGK alpha) through 67LR, contributing to improvement of diabetic nephropathy D Hayashi, L Wang, K Yagi, S Ueda, M Yamanoue, N Saito, N Emoto, ... JOURNAL OF PHARMACOLOGICAL SCIENCES 133 (3), S99-S99, 2017 | | 2017 |
Screening of novel diacylglycerol kinase alpha (DGK alpha) activator to develop drugs improving diabetic nephropathy D Hayashi, K Liu, S Ueda, M Yamanoue, F Sakane, Y Shirai JOURNAL OF PHARMACOLOGICAL SCIENCES 128 (3), S102-S102, 2015 | | 2015 |